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FGFR Fibroblast Growth Factor Receptor

Cat.No.  Name Information
M1721 AZD4547 AZD4547 (Fexagratinib) is a potent, selective and orally active pan-FGFR inhibitor with IC50s of 0.2. 2.5, 1.8 and 165 nM for FGFR1, 2, 3 and 4, respectively.
M1840 BGJ398 (Infigratinib) BGJ398 (Infigratinib) is a potent and selective FGFR kinase inhibitor with IC50 values of 0.9 nM, 1.4 nM, 1 nM and 60 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.
M9715 Erdafitinib Erdafitinib (JNJ-42756493) is a potent and selective orally bioavailable, pan FGFR inhibitor with potential antineoplastic activity.
M1875 PD173074 PD173074 is a selective FGFR1 and FGFR3 inhibitor with IC50 values of 5, 21.5, ~100, 17600 and 19800 nM for FGFR3, FGFR1, VEGFR2, PDGFR and c-Src respectively.
M54591 SAR-442501 SAR-442501 is a novel anti-FGFR3 monoclonal antibody for studies related to achondroplasia (ACH).
M54590 TYRA-200 TYRA-200 is an FGFR1/2/3 (FGFR2 mutation) inhibitor.
M54589 TYRA-300 TYRA-300 is an orally active, selective FGFR3 inhibitor for the study of chondrodysplasia.
M54477 VSPPLTLGQLLS VSPPLTLGQLLS is a small peptide FGFR3 inhibitor, peptide P3, inhibits FGFR3 phosphorylation.
M45218 ABSK061 ABSK061 is an orally active, selective, small molecule FGFR2/3 inhibitor for studies related to solid tumors.
M45217 ABSK121 ABSK121 is an orally active, highly selective small molecule FGFR inhibitor.
M45216 ABSK012 ABSK012 is a highly selective FGFR4 inhibitor with antitumor activity for studies related to soft tissue sarcoma (STS).
M43509 S6K2-IN-1 S6K2-IN-1 is a S6K2 inhibitor (IC50: 22 nM).
M43508 FGFR4-IN-14 FGFR4-IN-14 is a FGFR4 inhibitor (IC50: 2.4 nM.
M43507 FGFR1 inhibitor-10 FGFR1 inhibitor-10 is an FGFR1 inhibitor (IC50: 28 nM).
M43506 FGFR1 inhibitor-8 FGFR1 inhibitor-8 is a FGFR1 inhibitor (IC50s: 0.5 nM).
M43505 Formononetin-d3-1 Formononetin-d3-1 is the deuterium-labeled Formononetin.
M43504 FGFR1 inhibitor-9 FGFR1 inhibitor-9 is an FGFR1 inhibitor (IC50s: 0.85 nM).
M43503 FGFR4-IN-16 FGFR4-IN-16 (CY-15-2) is a covalent inhibitor of FGFR-4 for cancer research.
M43502 FGFR1 inhibitor 7 FGFR1 inhibitor 7 is an inhibitor of FGFR1 Tyrosine Kinase with IC50 value of 0.33 nM.
M43501 Resigratinib Resigratinib (KIN-3248) is a FGFR tyrosine kinase inhibitor, with antineoplastic effect.
M43500 LC-MB12 LC-MB12 is an orally active PROTAC compound targets FGFR2 degradation with a DC50 of 11.8 nM.
M43499 Irpagratinib Irpagratinib (ABSK011) is a potentially best-in-class, orally active fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor targeting FGFR4 (IC50<10 nM).
M40986 NGM-313 NGM-313 is a β-Klotho/FGFR1c-targeted monoclonal antibody for studies related to non-alcoholic steatohepatitis (NASH).
M40984 BOS-580 BOS-580 is an FGF21 analog and modulator for studies related to non-alcoholic steatohepatitis (NASH).




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