| Cat.No. | Name | Information |
|---|---|---|
| M66215 | Recombinant Human DHFR Protein (E. coli, N-His) | DHFR protein, a pivotal enzyme in folate metabolism, is crucial for multiple pathways. It catalyzes reactions essential for de novo mitochondrial thymidylate biosynthesis, de novo glycine and purine synthesis, and DNA precursor synthesis. |
| M66199 | Recombinant Human ERBB3/HER3 (HEK293, C-Fc) | ERBB3/HER3 belongs to the protein kinase superfamily,tyr protein kinase family and EGF receptor subfamily.It contains 1 protein kinase domain and it is expressed in Epithelial tissues and brain. |
| M66165 | Recombinant Mouse MPO/Myeloperoxidase (HEK293, C-10His) | Myeloperoxidase (MPO) is a heme-containing enzyme belonging to the XPO subfamily of peroxidases. MPO activity results in protein nitrosylation and the formation of 3-chlorotyrosine and dityrosine crosslinks. MPO is also associated with a variety of other diseases, and inhibits vasodilation in inflammation by depleting the levels of NO. |
| M66164 | Recombinant Human MPO/Myeloperoxidase (HEK293, C-10His) | Myeloperoxidase (MPO) is a heme-containing enzyme belonging to the XPO subfamily of peroxidases. MPO activity results in protein nitrosylation and the formation of 3-chlorotyrosine and dityrosine crosslinks. MPO is also associated with a variety of other diseases, and inhibits vasodilation in inflammation by depleting the levels of NO. |
| M66010 | Recombinant Mouse ERBB3/HER3 (HEK293, C-6His) | ERBB3/HER3 is an enzyme belongs to the protein kinase superfamily, tyr protein kinase family and EGF receptor subfamily. |
| M66009 | Recombinant Human ERBB3/HER3 (HEK293, C-6His) | ERBB3/HER3 is an enzyme belongs to the protein kinase superfamily, tyr protein kinase family and EGF receptor subfamily. |
| M59331 | Recombinant Human MAPK3 Protein (E. coli, N-His) | MAPK3 is an important serine/threonine kinase in the MAP kinase pathway and cooperates with MAPK1/ERK2 to activate the MAPK/ERK cascade. Stimulated by KIT and KITLG/SCF, this pathway plays a key role in cell growth, adhesion, survival, and differentiation. |
| M59330 | Recombinant Human MAPK14 Protein (E. coli, N-His) | MAPK14 is an important serine/threonine kinase in the MAP kinase pathway. It can respond to stimuli such as cytokines or stress and directly activate transcription factors. In this cascade, p38 MAPK each phosphorylates approximately 200 to 300 substrates, including the downstream kinases RPS6KA5/MSK1 and RPS6KA4/MSK2, which are critical for immediate early gene induction. |
| M59329 | Recombinant Human MAPK8 Protein (E. coli, N-His) | MAPK8 is a multifunctional serine/threonine protein kinase that complexly regulates multiple cellular processes, including cell proliferation, apoptosis, and differentiation. MAPK8 is activated by MAP2K4/MKK4 and MAP2K7/MKK7, phosphorylates AP-1 components, and affects transcriptional activity. |
| M59216 | Recombinant Mouse LDHA Protein (HEK293, C-6His) | Mouse Lactate dehydrogenase A (LDHA) is a member of the LDH/MDH superfamily and LDH family. LDHA can promote the Warburg effect to produce lactate and Adenosine Triphosphate (ATP) in aerobic conditions. LDHA is found in most somatic tissues, though predominantly in muscle tissue and tumours. LDHA plays an important role in the development, invasion and metastasis of malignancies. |
| M59166 | Recombinant Human LDH-B (E. coli, N-6His) | L-Lactate Dehydrogenase B Chain (LDH-B) is a member of the lactate dehydrogenase family. LDH-B is an oxidoreductase that catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. It converts pyruvate to lactate when oxygen is absent or in short supply and it performs the reverse reaction during the Cori cycle in the liver. |
| M59026 | Recombinant Human TIMP-1 (HEK293, C-6His) | Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) is a member of TIMP family. The homologous proteins of TIMPs regulate the activity of matrix metalloproteinases (MMPs), including inhibition of active MMPs, proMMP activation, cell growth promotion, matrix binding, inhibition of angiogenesis and the induction of apoptosis. |
| M58979 | Recombinant Human DPP-4/CD26 Protein (HEK293, N-hFc) | Dipeptidyl peptidase-4 (DPP4) is a serine exopeptidase belonging to the S9B protein family. The enzyme is a type II transmembrane glycoprotein, expressed on the surface of many cell types. It is also present in serum and other body fluids in a truncated form (sCD26/DPPIV). As both a regulatory enzyme and a signalling factor, DPP4 has been evaluated and described in many studies. DPP4 inhibition results in increased blood concentration of the incretin hormones glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP). |
| M58611 | Recombinant Human SOD1 Protein (E. coli, N-6His) | SOD1 binds copper and zinc ions and is one of three isozymes responsible for destroying free superoxide radicals in the body. SOD1 neutralizes supercharged oxygen molecules, which can damage cells if their levels are not controlled. The enzyme protects the cell against dangerous levels of superoxide. |
| M58610 | Recombinant Human SOD2 (HEK293, C-6His) | SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic superoxide, a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. |
| M55681 | Recombinant Human MMP13 Protein (E. coli, N-His) | The MMP-13 protein plays a role in the degradation of extracellular matrix proteins, especially fibrillar collagen, fibronectin, TNC, and ACAN. It cleaves triple-helical collagen, preferentially cleaves type II collagen, and can also target other collagen types. |
| M55549 | Recombinant Mouse DPP-4/CD26 Protein (HEK293, N-hFc) | Dipeptidyl peptidase-4 (DPP4, CD26) is a serine exopeptidase belonging to the S9B protein family. The enzyme is a type II transmembrane glycoprotein, expressed on the surface of many cell types. It is also present in serum and other body fluids in a truncated form (sCD26/DPPIV). |
| M55024 | Recombinant Human DPP4/CD26 (HEK293, C-6His) | DPP4/CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. DPP4/CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. |
| M43971 | Recombinant Human MMP12 Protein (E. coli) | Matrix metalloproteinase-12 (MMP12) is a macrophage-secreted elastase that is highly induced in the liver and lung in response to S. mansoni eggs and contains four hemopexin-like domains. MMP12 is a proteolytic enzyme responsible for the cleavage of plasminogen to angiotensin, which has an angiostatic effect. |
| M43970 | Recombinant Human MMP-8 Protein (HEK293, C-His) | Matrix metalloproteinase-8 (MMP-8) is a member of the peptidase M1A family. MMP-8 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in dгυg development. |
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