Inhibitor
| Cat.No. | Name | Information |
|---|---|---|
| M10346 | L-Glutamic acid | L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). |
| M18309 | p-Hydroxy-cinnamic acid | p-Hydroxy-cinnamic acid inhibits platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively. |
| M6687 | Docosahexaenoic acid (Oil) | Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. Docosahexaenoic acid is a RXR agonist. |
| M9953 | Taurocholic acid | Taurocholic acid (N-Choloyltaurine) is a bile acid, which can be used in the emulsification of fats. |
| M10168 | L-Lactic acid | L-Lactic acid is an organic acid, which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. |
| M31283 | Glucose oxidase | Glucose oxidase (GOD) is an oxidoreductase enzyme that inhibits the proliferation of cancer cells by reacting with intracellular oxygen (O2) and β-D-glucose to produce hydrogen peroxide (H2O2) and gluconic acid, thereby cutting off the source of nutrients for cancer cells. |
| M9076 | NADPH tetrasodium salt | NADPH tetrasodium salt is a cofactor, used to donate electrons and a hydrogens to reactions catalyzed by some enzymes. NADPH tetrasodium salt functions as an important cofactor in a variety of metabolic and biosynthetic pathways. NADPH tetrasodium salt plays a vital role in the biosynthesis of agents, chiral alcohols, fatty acids and biopolymers, while also being required for lipid biosynthesis, biomass formation, and cell replication. |
| M14386 | Maltol | Maltol, a type of aromatic compound, exists in high concentrations in red ginseng. Maltol is a potent antioxidative agent and typically is used to enhance flavor and preserve food. |
| M9905 | ATP disodium salt hydrate | ATP disodium salt hydrate is a disodium salt hydrate form of adenosine-triphosphate that is used in cells as a coenzyme. |
| M3292 | Adenosine | Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond. |
| M29951 | Ketotifen | Ketotifen (HC 20-511) is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. Ketotifen can block 6-phosphogluconate dehydrogenase (PGD) in vitro. Ketotifen also has antiviral activity against SARS-CoV-2 and Influenza virus. Ketotifen can be used to the research of autoimmune encephalomyelitis (EAE) and asthma attack prevention. |
| M29943 | T-2 Triol | T-2 Triol is a trichothecene mycotoxin derived by the metabolism of T-2 toxin. It is less toxic than T-2 toxin. T-2 Triol major metabolites are evaluated in broiler chickens with Half-lives (t1/2λz), Peak plasma concentrations (Cmax) and Tmax values of 9.6 mins, 563 ng/ml , 2.5 mins, respectively. |
| M29870 | Asymmetric dimethylarginine | Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS), and functions as a marker of endothelial dysfunction in a number of pathological states. |
| M29831 | 10-Formyltetrahydrofolic acid | 10-Formyltetrahydrofolic acid is a form of tetrahydrofolic acid that acts as a donor of formyl groups in anabolism. 10-Formyltetrahydrofolic acid can be used as a substrate for formyltransferase reactions and is involved in the biosynthesis of purines. |
| M29687 | 5-Bromo-L-tryptophan | 5-Bromo-L-tryptophan is an α-amino acid derivative that can be found in Semenospongia sp.. |
| M29674 | (-)-Mesembrine | (-)-Mesembrine, a psychoactive alkaloid, is a partial racemate in S. strictum and S. tortuosum in smaller amounts. |
| M29488 | (Rac)-Salvianic acid A | (Rac)-Salvianic acid A ((Rac)-Danshensu), a phenolic acids, is an efficient radical scavenger and antioxidant. |
| M29472 | Diacetoxyscirpenol | Diacetoxyscirpenol (DAS) is a trichothecene mycotoxin, a secondary metabolite product of fungi. Diacetoxyscirpenol (DAS) consumption induces haematological disorders (neutropenia, aplastic anemia) in human and animals. |
| M29123 | Adenosine 5'-diphosphate sodium salt | Adenosine 5'-diphosphate (ADP) sodium salt is a nucleoside diphosphate, which is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate sodium salt induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors. |
| M28834 | L-hydroxylysine dihydrochloride | L-hydroxylysine dihydrochloride ((2S,5R)-5-Hydroxylysine dihydrochloride), an amino acid, is exclusive to collagen protein, which is formed by posttranslational hydroxylation of some lysine residues. |
| M28695 | Creatine riboside | Creatine riboside is a urinary metabolite and is a diagnostic and prognostic biomarker of lung cancer. |
| M28528 | Seco Rapamycin sodium salt | Seco Rapamycin sodium salt is the ring-opened product of Rapamycin. Seco-rapamycin is reported not to affect the mTOR function. |
| M28521 | Niraparib metabolite M1 | Niraparib metabolite M1 is a metabolite of niraparib, and the latter one acts as a novel poly(ADP-Ribose) polymerase (PARP) inhibitor. |
| M28516 | Seco Rapamycin | Seco Rapamycin (Secorapamycin A) is the ring-opened product of Rapamycin. Seco-rapamycin is reported not to affect the mTOR function. |
| M28484 | Dehydrocholate sodium | Dehydrocholic sodium is a hydrocholeretic, increasing bile output to clear increased bile acid load. |
| M28325 | 16α-Hydroxyprednisolone | 16α-Hydroxyprednisolone is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid budesonide via cytochrome P450 3A (CYP3A) enzymes. |
| M28210 | Lobeline sulfate | Lobeline sulfate (α-Lobeline sulfate; L-Lobeline sulfate) is a nonstimulant medication that can alter dopamine uptake in brain. Lobeline sulfate (α-Lobeline sulfate; L-Lobeline sulfate) inhibits nicotine-induced hyperactivity and is effective in smoking cessation. |
| M28196 | 12-Hydroxynevirapine | 12-Hydroxynevirapine (12-hydroxy-NVP; 12-OH-NVP) is a major oxidative metabolite of Nevirapine. Nevirapine is a non-nucleoside reverse transcriptase inhibitor indicated for the HIV-1 infections. Nevirapine causes idiosyncratic hepatotoxicity and mild-to-severe skin rashes. 12-Hydroxynevirapine, a non-reactive metabolite, can be bioactivated by sulphotransferases (SULTs) in the liver and skin, yielding the reactive species 12-Sulphoxy-nevirapine. |
| M27739 | SMND-309 | SMND-309 is a metabolite of salvianolic acid B, and exhibits neuroprotective effects in cultured neurons and in permanent middle cerebral artery occlusion rats. |
| M27691 | NSC 90469 | NSC 90469 is an endogenous metabolite. |
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