Inhibitor
| Cat.No. | Name | Information |
|---|---|---|
| M10346 | L-Glutamic acid | L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). |
| M18309 | p-Hydroxy-cinnamic acid | p-Hydroxy-cinnamic acid inhibits platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively. |
| M6687 | Docosahexaenoic acid (Oil) | Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. Docosahexaenoic acid is a RXR agonist. |
| M9953 | Taurocholic acid | Taurocholic acid (N-Choloyltaurine) is a bile acid, which can be used in the emulsification of fats. |
| M10168 | L-Lactic acid | L-Lactic acid is an organic acid, which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. |
| M31283 | Glucose oxidase | Glucose oxidase (GOD) is an oxidoreductase enzyme that inhibits the proliferation of cancer cells by reacting with intracellular oxygen (O2) and β-D-glucose to produce hydrogen peroxide (H2O2) and gluconic acid, thereby cutting off the source of nutrients for cancer cells. |
| M9076 | NADPH tetrasodium salt | NADPH tetrasodium salt is a cofactor, used to donate electrons and a hydrogens to reactions catalyzed by some enzymes. NADPH tetrasodium salt functions as an important cofactor in a variety of metabolic and biosynthetic pathways. NADPH tetrasodium salt plays a vital role in the biosynthesis of agents, chiral alcohols, fatty acids and biopolymers, while also being required for lipid biosynthesis, biomass formation, and cell replication. |
| M14386 | Maltol | Maltol, a type of aromatic compound, exists in high concentrations in red ginseng. Maltol is a potent antioxidative agent and typically is used to enhance flavor and preserve food. |
| M9905 | ATP disodium salt hydrate | ATP disodium salt hydrate is a disodium salt hydrate form of adenosine-triphosphate that is used in cells as a coenzyme. |
| M3292 | Adenosine | Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond. |
| M59257 | 3-Methyluridine | 3-Methyluridine is a methylated nucleotide present in ribosomal RNA (rRNA), mainly targeting specific base sites of RNA molecules such as 23S rRNA. 3-Methyluridine can introduce a methyl group at the N3 position of uracil, affecting the secondary structure stability and base pairing ability of RNA, and regulating ribosome function. |
| M59179 | 1a,1b-dihomo Prostaglandin F2α | 1a,1b-dihomo Prostaglandin F2α (1a,1b-dihomo PGF2α) is a hypothetical product of adrenic acid in the COX pathway. |
| M59161 | Dihydrothymine | Dihydrothymine (5,6-Dihydro-5-methyluracil) is an intermediate breakdown product of thymine, comes from animal or plants. |
| M59121 | Lithium acetoacetate | Lithium acetoacetate (Acetoacetic acid lithium) is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. Lithium acetoacetate induces oxidative stress by decreasing the mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), increasing MDA content, and inhibiting very low density lipoprotein (VLDL) assembly by downregulating apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR), leading to triglyceride (TG) accumulation in hepatocytes. |
| M59096 | Gentisuric Acid | Gentisuric Acid is a metabolite of Aspirin, it is a substrate of α-amidating monooxygenase (PAM). Gentisuric acid prevents DNA-damage by Mitomycin C. |
| M59095 | 5α-Dihydroprogesterone | 5α-Dihydroprogesterone (5a-Pregnane-3,20-dione) is the endogenous progesterone metabolite. 5α-Dihydroprogesterone (5a-Pregnane-3,20-dione) decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerizes F-actin in MCF-7 breast cancer cells. |
| M59086 | Adenosine 2',3'-cyclic phosphate sodium | Adenosine 2',3'-cyclic phosphate sodium serves as an extracellular source of adenosine. The release of extracellular 2′,3′-cAMP occurs in response to injury. 2′,3′-cAMP may be used to study the distribution and specificity of its degrading enzymes in the context of unique biological activities. 2′,3′-cAMP may also be used to study apoptosis induced at the level of mitochondrial permeability transition pores. 2′,3′-cAMP is converted into 2′-AMP and 3′-AMP which inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. |
| M59073 | 6α-Hydroxy Paclitaxel | 6α-Hydroxy Paclitaxel is a primary metabolite of Paclitaxel. 6α-Hydroxy Paclitaxel (6-Hydroxytaxol) retains a time-dependent effect on organic anion-transporting polypeptides 1B1/SLCO1B1 (OATP1B1) with similar inhibition potency to Paclitaxel, whereas it no longer showed time-dependent inhibition of OATP1B3. |
| M59035 | Casein (from bovine milk) | Casein is a phosphorus-containing complex protein with α-casein and β-casein as its main components. Casein is an orally active phosphoprotein that can be separated into various electrophoretic components, such as α2-Casein, κ-Casein, β-casein, and γ-casein. Casein can be used in biochemical research, to formulate biological culture media, and as a thickener, emulsifier and stabiliser. |
| M59027 | Palmitic acid-13C16 | Palmitic acid-13C16 is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. |
| M59016 | Methionine sulfoximine | Methionine sulfoximine (2-Amino-4-(S-methylsulfonimidoyl)butanoic acid) is an irreversible inhibitor of glutamine synthetase. Methionine sulfoximine is able to affect the metabolism of glutamate and glutamine. |
| M59010 | L-Glutamine-15N2 | L-Glutamine-15N2 is the 15N-labeled L-Glutamine. L-Glutamine is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells. |
| M59004 | 4-Hydroxyestradiol | 4-Hydroxyestradiol (4-Hydroxy-17β-estradiol) is an endogenous metabolite of Estradiol. 4-Hydroxyestradiol inhibits the binding of Estradiol to the estrogen receptor in a competitive manner, with a Ki of 0.48 nM. 4-Hydroxyestradiol is carcinogenic and shows mutagenic activity in breast epithelial cells. |
| M58977 | Isolithocholic acid | Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate. |
| M58961 | 1-Palmitoyl-sn-glycero-3-phosphocholine | 1-Palmitoyl-sn-glycero-3-phosphocholine is an lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the research of atherosclerosis. |
| M58956 | L-Citrulline DL-Malate | L-Citrulline DL-malate is an organic compound commonly used as a nutritional supplement. It boosts the body's production of nitrogen oxides, improves circulation and athletic performance, and reduces muscle fatigue. In addition, L-Citrulline DL-malate can be used in the field of agriculture to enhance plant immunity. |
| M58955 | Creatine-d3 | Creatine-d3 is the deuterium labeled Creatine. Creatine is an endogenous amino acid derivative, which plays an important role in cellular energy, especially in muscle and brain. |
| M58946 | D-Glucose-13C6 | D-Glucose-13C6 can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard. |
| M58714 | D-Alanine | D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR. |
| M58702 | Quercetin 7-glucuronide | Quercetin 7-glucuronide can inhibit LDL oxidation. Quercetin 7-glucuronide (Quercetin 7-O-β-glucuronide) can be isolated from Madagascarian Uncarina species. |
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