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Dopamine Receptor Dopamine Receptor

Cat.No.  Name Information
M5686 Haloperidol Haloperidol is a potent dopamine D2 receptor antagonist.
M9049 MPTP hydrochloride MPTP hydrochloride is dehydrogenated in nigrostriatal cells to generate MPP+, which in turn inhibits mitochondrial complex enzymes and contributes to cell death. MPTP hydrochloride can be used to construct animal models of Parkinson's disease.
M2472 Bromocriptine Mesylate Bromocriptine, an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes.
M20535 Chlorpromazine Chlorpromazine is an orally active, blood-brain barrier-transparent D2 dopamine receptors and 5-HT2A antagonist. Chlorpromazine also blocks hNav1.7 channels (IC50=25.9 μM; concentration-dependent) and HERG potassium channels (IC50=21.6 μM).
M6370 A 68930 hydrochloride A 68930 hydrochloride is a potent, selective D 1-like agonist.
M6366 A 412997 dihydrochloride A 412997 dihydrochloride is a selective D 4 agonist.
M6279 Laropiprant Laropiprant is a potent, selective DP1 receptor antagonist with Ki value of 0.57 nM, and exhibits > 1,000 fold selectivity over DP2 receptor (Ki=0.75 μM).
M6196 Fupentixol dihydrochloride Flupentixol dihydrochloride, a thioxanthene drug, is used in therapy of schizophrenia as well as in anxiolytic and depressive disorders.
M5984 Sulpiride Sulpiride is a dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid.
M5914 rac-Rotigotine (Hydrochloride) rac-Rotigotine Hcl is a high potency and selectivity agonist for D-2 receptor with Ki of 0.69 nM.
M5903 Promazine HCl Promazine (hydrochloride) is a D2 dopamine receptor antagonist, belongs to the phenothiazine class of antipsychotics, used to treat schizophrenia.
M5900 Prochlorperazine dimaleate salt Prochlorperazine dimaleate is a dopamine (D2) receptor antagonist.
M5891 Pramipexole dihydrochloride Pramipexole 2Hcl is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively.
M5872 Perphenazine Perphenazine is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.
M5854 SB 277011 Hydrochloride Ligands acting as DRD3 antagonists (SB 277011-A) has shown some promise for reducing the influence of drug-associated cues on motivational behaviour.
M5848 Paliperidone Paliperidone, the main active metabolite of Risperidone, is a dopamine D2 antagonist and 5-HT2A antagonist. Paliperidone is also active as an antagonist at α1 and α2 adrenergic receptors and H1-histaminergic receptors.
M5796 Molindone HCl Molindone is an antipsychotic compound used to study schizophrenia that reduces psychosis by blocking the action of dopamine in the brain.
M5739 Levosulpiride Levosulpiride is a selective antagonist for D2 dopamine receptors used as an antipsychotic and prokinetic agent.
M5642 Fenoldopam mesylate Fenoldopam is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.
M5525 Clebopride malate Clebopride malate is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders.
M5467 Brexpiprazole Brexpiprazole is a novel D2 dopamine and serotonin 1A partial agonist, called serotonin-dopamine activity modulator (SDAM), and a potent antagonist of serotonin 2A receptors, noradrenergic alpha 1B and 2C receptors.
M5410 Amisulpride Amisulpride is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.
M5350 Octopamine hydrochloride Octopamine (OA), a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates.
M5198 Fluphenazine dihydrochloride Fluphenazine dihydrochloride is a phenothiazine-class D1DR and D2DR inhibitor.




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