| Cat.No. | Name | Information |
|---|---|---|
| M9370 | Recombinant Human TNF α (HEK293, C-His) | Recombinant Human TNF α (HEK293, C-His) plays an important role in growth regulation, differentiation, inflammatory response, viral replication, tumorigenesis, autoimmune diseases, and viral, bacterial, fungal, and parasitic infections. |
| M9413 | Recombinant Human VEGF165 Protein (HEK293, C-His) | Recombinant Human VEGF165 Protein (HEK293, C-His) is a powerful growth and angiogenic cytokine, it promotes the proliferation and survival of endothelial cells, promotes angiogenesis and vascular permeability. |
| M10922 | Recombinant Mouse TGF-beta 1 Protein (HEK293) | Recombinant Mouse TGF-beta 1 Protein is a multifunctional cytokine that controls many biological processes including immunity, differentiation, tumor suppression, tumor metastasis, aging, migration, wound healing, apoptosis, cell division, adipogenesis, and osteogenesis. ED50 is 5-25 pg/ml |
| M9391 | Recombinant Human TGF-β1 (CHO) | Recombinant Human TGF-β1 regulates cell proliferation, growth, differentiation and cells movement. TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. |
| M9241 | Recombinant Human EPO Protein (CHO) | Erythropoietin (EPO) is a glycoprotein hormone known primarily for its role in erythropoiesis, which is responsible for stimulating the proliferation and differentiation of erythroid progenitor cells. |
| M9402 | Recombinant Human PDGF-BB Protein (HEK293, C-His) | Recombinant Human PDGF-BB Protein (HEK293) |
| M9987 | Recombinant Human PDGF-AA Protein (HEK293) | Recombinant Human PDGF-AA Protein (HEK293) is a potent mitogen for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. |
| M9981 | Recombinant Human IL-11 Protein (E. coli) | Recombinant Human IL-11 Protein is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. |
| M21094 | Recombinant Rat IL-1β (E. coli) | Interleukin-1β (IL-1β) is a non-secreted pro-inflammatory cytokine produced primarily by activated macrophages as well as neutrophils, epithelial cells and endothelial cells. Measured by a cell proliferation assay using mouse D10S cells, the ED50 is < 10.0 pg/ml, corresponding to a specific activity of > 1.0 × 108 units/mg. |
| M10022 | Recombinant Mouse GM-CSF Protein (CHO) | Recombinant GM-CSF Protein is a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. GM-CSF is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory. ED50 < 0.05 ng/ml, measured in a cell proliferation assay using mouse FDC-P1 cells, corresponding to a specific activity of > 2.0 × 107 units/mg. |
| M66191 | Recombinant Human Angiopoietin-1/ANGPT1 Protein (HEK293, N-Fc) | Angiopoietin-1 (Ang-1) is a secreted glycoprotein that plays a critical role in the development and maintenance of the vascular system. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. Angiopoietin-1 can protect against pulmonary arterial hypertension, reduce the extent of fibrosis and remodeling in infarcted diabetic myocardium, and enhance tumor progression and metastasis. |
| M66181 | Recombinant Rat IL-3 Protein (Baculovirus-Insect, C-His) | IL-3 is a potent growth-promoting cytokine that belongs to the group of interleukins. It stimulates basophils, eosinophils, and monocytes, and promotes neural cell proliferation. IL-3 inhibits osteoclast differentiation and activates JAK2-STAT5 pathway. It is involved in a variety of cell activities such as cell growth, differentiation, and apoptosis. IL3/IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders. |
| M66001 | Recombinant Human Laminin 521 Protein (HEK293) | Laminins are large molecular weight glycoproteins constituted by the assembly of three disulfide-linked polypeptides, the α, β and γ chains. Laminin 521 Protein is often used as a substrate component for stem cell culture and can maintain the self-renewal capacity of embryonic stem cells and induced pluripotent stem cells. Laminin 521 Protein plays a key role in cell adhesion, migration, differentiation, and the development and homeostasis maintenance of tissues and organs. |
| M65750 | Recombinant Human AREG Protein (E. coli) | Amphiregulin (AREG) is a single-pass membrane protein related to Epidermal Growth Factor (EGF) and Transforming Growth Factor Alpha. AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. |
| M65739 | Recombinant Mouse Osteopontin/SPP1 Protein (HEK293, C-His) | Osteopontin/SPP1 is a secreted multifunctional glycoprotein. Its putative functions include roles in bone metabolism, immune regulation, wound healing, cell survival, and tumor progression. Osteopontin/SPP1 acts as a cytokine that is involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10. |
| M65715 | Recombinant Human Laminin 511 Protein (HEK293) | Laminins belong to the laminin family and Laminins are the important components of the extracellular matrix (ECM). Laminins are indispensable building blocks for cellular networks physically bridging the intracellular and extracellular compartments and relaying signals critical for cellular behavior, and for extracellular polymers determining the architecture and the physiology of basement membranes. |
| M59306 | Recombinant Mouse CCL1/TCA-3 Protein (HEK293, C-hFc-His, Active) | Recombinant Mouse CCL1/TCA-3 Protein is a cytokine that mediates inflammatory immune responses, viral infections, and tumorigenesis by interacting with the CCR8 chemokine receptor on the cell surface and attracting monocytes, natural killer cells, and immature B-cell nuclear dendritic cells. |
| M59297 | Recombinant Rabbit TNF alpha (E. coli) | Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. |
| M59294 | Recombinant Mouse HB-EGF (E. coli) | Heparin-binding EGF-like growth factor (HB-EGF) is synthesized as a membrane-anchored mitogenic and chemotactic glycoprotein. It has been shown to play a role in wound healing, cardiac hypertrophy and heart development and function. The transmembrane form of HB-EGF is the unique receptor for diptheria toxin and functions in juxtacrine signaling in cells. |
| M59266 | Recombinant Rat IFN-γ (CHO) | Interferon-γ (IFN-γ) is a cytokine produced primarily by T-lymphocytes and natural killer cells. IFN-γ signaling does diverse biological functions primarily related to host defense and immune regulation, including antiviral and antibacterial defense, apoptosis, inflammation, and innate and acquired immunity. |
| M59265 | Recombinant Mouse IL-25 (E. coli, C-His) | Interleukin 25 (IL-25) is a cytokine with proinflammatory and anti-inflammatory effects. It can induce NF-κB activation, and stimulate the production of IL-8, which is the major chemotactic substance of neutrophils. |
| M59242 | Recombinant Mouse CXCL4/PF4 Protein (E. coli, N-His) | CXCL4/PF4 is a small cytokine belonging to the CXC chemokine family. CXCL4/PF4 is released from the alpha-granules of activated platelets and binds with high affinity to heparin. CXCL4/PF4 has a role in inflammation and wound repair. CXCL4/PF4 neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. CXCL4 is chemotactic for neutrophils and monocytes. It inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form. |
| M59177 | Recombinant Mouse IL-6 (E. coli, C-His) | Interleukin-6 (IL-6) plays fundamental role in the acute phase response, inflammation, bone metabolism, lymphocyte differentiation and cancer progression. |
| M58941 | Recombinant Human GDF-15 Protein (HEK293 N-hFc) | Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily. GDF-15 has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF-15 overexpression arising from an expanded erythroid compartment contributes to iron overload in thalassemia syndromes by inhibiting hepcidin expression. |
| M58709 | Recombinant Human FGFR1 Protein (HEK293, C-His) | FGFR1, also known as CD331, is a full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. |
| M58708 | Recombinant Human FGFR2 Protein (HEK293, C-His) | FGFR2, also known as CD332, acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. FGFR2 plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. It also promotes cell proliferation in keratinocytes and imature osteoblasts, but promotes apoptosis in differentiated osteoblasts. |
| M58696 | Recombinant Mouse BMP-4 Protein (E. coli, C-His) | Bone Morphogenetic Protein-4 (BMP-4) is a critical signaling molecule required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. BMP-4 is secreted from the dorsal portion of the notochord, and it acts in concert with sonic hedgehog to establish a dorsal-ventral axis for the differentiation of later structures. |
| M58686 | Recombinant Human Coagulation Factor X (HEK293, C-Fc) | Coagulation factor X, belongs to the peptidase S1 family. Coagulation factor X is initially synthesized in the liver. Coagulation factor X is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. |
| M58627 | Recombinant Human FGF-8b Protein (E. coli) | Recombinant Human FGF-8b Protein is a heparin-binding growth factor, which plays a core role in prenatal development, postnatal growth and regeneration of various tissues by promoting cell proliferation and other effect. |
| M58618 | Recombinant Rat GDNF Protein (Baculovirus-Insect, N-His) | GDNF is an important member of the GDNF family of ligands. GDNF plays a key role in the promotion of the survival of dopaminergic neurons. GDNF is a highly conserved neurotrophic factor. The recombinant form of this protein also promotes the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. GDNF also regulates kidney development and spermatogenesis, and it affects alcohol consumption. |
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