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Cytokines and Growth Factors Cytokines and Growth Factors

Cat.No.  Name Information
M9370 Recombinant Human TNF α (HEK293, C-His) Recombinant Human TNF α (HEK293, C-His) plays an important role in growth regulation, differentiation, inflammatory response, viral replication, tumorigenesis, autoimmune diseases, and viral, bacterial, fungal, and parasitic infections.
M9413 Recombinant Human VEGF165 Protein (HEK293, C-His) Recombinant Human VEGF165 Protein (HEK293, C-His) is a powerful growth and angiogenic cytokine, it promotes the proliferation and survival of endothelial cells, promotes angiogenesis and vascular permeability.
M10922 Recombinant Mouse TGF-beta 1 Protein (HEK293) Recombinant Mouse TGF-beta 1 Protein is a multifunctional cytokine that controls many biological processes including immunity, differentiation, tumor suppression, tumor metastasis, aging, migration, wound healing, apoptosis, cell division, adipogenesis, and osteogenesis. ED50 is 5-25 pg/ml
M9391 Recombinant Human TGF-β1 (CHO) Recombinant Human TGF-β1 regulates cell proliferation, growth, differentiation and cells movement. TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis.
M9241 Recombinant Human EPO Protein (CHO) Erythropoietin (EPO) is a glycoprotein hormone known primarily for its role in erythropoiesis, which is responsible for stimulating the proliferation and differentiation of erythroid progenitor cells.
M9402 Recombinant Human PDGF-BB Protein (HEK293, C-His) Recombinant Human PDGF-BB Protein (HEK293)
M9987 Recombinant Human PDGF-AA Protein (HEK293) Recombinant Human PDGF-AA Protein (HEK293) is a potent mitogen for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells.
M9981 Recombinant Human IL-11 Protein (E. coli) Recombinant Human IL-11 Protein is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts.
M21094 Recombinant Rat IL-1β (E. coli) Interleukin-1β (IL-1β) is a non-secreted pro-inflammatory cytokine produced primarily by activated macrophages as well as neutrophils, epithelial cells and endothelial cells. Measured by a cell proliferation assay using mouse D10S cells, the ED50 is < 10.0 pg/ml, corresponding to a specific activity of > 1.0 × 108 units/mg.
M10022 Recombinant Mouse GM-CSF Protein (CHO) Recombinant GM-CSF Protein is a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. GM-CSF is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory. ED50 < 0.05 ng/ml, measured in a cell proliferation assay using mouse FDC-P1 cells, corresponding to a specific activity of > 2.0 × 107 units/mg.
M10014 Recombinant Murine M-CSF Protein (HEK 293, C-His) Recombinant Murine M-CSF Protein (HEK 293) is a powerful hematopoietic factor produced by lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts.
M10011 Recombinant Human IFN-α 2b Protein (E. coli) Human IFN-α2a and -α2b (HEK293) are allelic variants of the same gene, the IFN-α subtype is classified as an intermediate/strong ISG inducer and has strong antiviral activity against influenza A virus.
M9999 Recombinant Human Noggin Protein (HEK293, C-His) Recombinant Human Noggin Protein (HEK293) can bind to ligands of the transforming growth factor-β family and regulate its activity by inhibiting its pathway with signal receptors.
M9990 Recombinant Human BMP-2 Protein (HEK293, C-Fc) Recombinant Human BMP-2 Protein (HEK293) is a powerful osteoinductive cytokine that can be combined with collagen and synthetic hydroxyapatite and other osteoconductive carriers to induce the formation of bone and cartilage.
M9987 Recombinant Human PDGF-AA Protein (HEK293) Recombinant Human PDGF-AA Protein (HEK293) is a potent mitogen for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells.
M9981 Recombinant Human IL-11 Protein (E. coli) Recombinant Human IL-11 Protein is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts.
M9865 Recombinant mouse IFN-γ (E. coli) Recombinant mouse IFN-γ (Murine IFN-γ) (E. coli)is an unstable interferon produced by CD4 and CD8 T lymphocytes and activated NK cells. IFN-γ receptors are present in most immune cells, and they respond to IFN-γ signaling by increasing the surface expression of class I γ proteins. ED50 < 0.15 ng/ml, measured by cytotoxicity assay using WEHI-279 cells.
M9759 Recombinant Human BMP-4 (HEK293, C-Fc) BMP-4 is involved in the development and maintenance of bone and cartilage. Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Measured by its ability to induce ATDC-5 cells to produce alkaline phosphatase, the ED50 is ≤50 ng/mL.
M9415 Recombinant Human EGF Protein (HEK293, C-His) Recombinant Human EGF Protein (HEK293) is an important class of growth factors.
M9413 Recombinant Human VEGF165 Protein (HEK293, C-His) Recombinant Human VEGF165 Protein (HEK293, C-His) is a powerful growth and angiogenic cytokine, it promotes the proliferation and survival of endothelial cells, promotes angiogenesis and vascular permeability.
M9406 Recombinant Human bFGF Protein (HEK293) Recombinant Human bFGF Protein (HEK293)
M9402 Recombinant Human PDGF-BB Protein (HEK293, C-His) Recombinant Human PDGF-BB Protein (HEK293)
M9391 Recombinant Human TGF-β1 (CHO) Recombinant Human TGF-β1 regulates cell proliferation, growth, differentiation and cells movement. TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis.
M9370 Recombinant Human TNF α (HEK293, C-His) Recombinant Human TNF α (HEK293, C-His) plays an important role in growth regulation, differentiation, inflammatory response, viral replication, tumorigenesis, autoimmune diseases, and viral, bacterial, fungal, and parasitic infections.
M9363 Recombinant Human IL-4 Protein (CHO, C-Fc) The role of Recombinant Human IL-4 Protein (CHO) in the induction of monocytes into DCs is to inhibit the overgrowth of macrophages, thereby directing monocyte differentiation toward DCs.
M9344 Recombinant Human GM-CSF (HEK293, C-His) Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor is a hematopoietic growth factor and immune modulator.
M9241 Recombinant Human EPO Protein (CHO) Erythropoietin (EPO) is a glycoprotein hormone known primarily for its role in erythropoiesis, which is responsible for stimulating the proliferation and differentiation of erythroid progenitor cells.
M66258 Recombinant Mouse IL-13 Protein (E. coli, C-His) IL-13 Protein is an immunoregulatory cytokine belonging to the IL-4/IL-13 family, a multifunctional cytokine whose main role is to reduce the inflammatory response. It is homologous to IL-4 and shares many of its biologic activities on mononuclear phagocytic cells, endothelial cells, epithelial cells, and B cells.
M66194 Recombinant Mouse Angiopoietin-2/ANGPT2 Protein (HEK293, C-Fc) Angiopoietin-2 (Ang-2; also ANGPT2) is a secreted glycoprotein that plays a complex role in angiogenesis and inflammation. Ang-2 may act as either a Tie-2 antagonist or agonist, depending upon its state of multimerization. Ang-2 functions as a pro-angiogenic factor, although it can also induce EC death and vessel regression. Upon its release from quiescent EC, it regulates vascular remodeling by promoting EC survival, proliferation, and migration and destabilizing the interaction between EC and perivascular cells.
M66193 Recombinant Human Angiopoietin-2/ANGPT2 Protein (HEK293, C-6His) Angiopoietin-2 (Ang-2; also ANGPT2) is a secreted glycoprotein that plays a complex role in angiogenesis and inflammation. Ang-2 may act as either a Tie-2 antagonist or agonist, depending upon its state of multimerization. Ang-2 functions as a pro-angiogenic factor, although it can also induce EC death and vessel regression. Upon its release from quiescent EC, it regulates vascular remodeling by promoting EC survival, proliferation, and migration and destabilizing the interaction between EC and perivascular cells.




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