| Cat.No. | Name | Information |
|---|---|---|
| M3326 | Memantine hydrochloride | Memantine hydrochloride is a CYP2B6 and CYP2D6 inhibitor for recombinant CYP2B6 and CYP2D6 with Ki of 0.51 nM and 94.9 μM, respectively. |
| M2079 | Chrysin | Chrysin is a naturally occurring flavone chemically extracted from the passion flowers Passiflora caerulea. |
| M4000 | (±)-Naringenin | (±)-Naringenin, a common dietary flavonoid abundantly present in fruits and vegetables, is believed to possess strong anti-proliferative properties and the ability to induce apoptosis in hepatoma cell lines. |
| M45022 | Terpinyl acetate | α-Terpinyl acetate is a monoterpene ester isolated from Laurus nobilis L. |
| M44872 | Harmidol hydrochloride | Harmalol hydrochloride, a beta carboline alkaloid, presents in several medicinal plants such as Peganum harmala. |
| M44743 | 4'-Methylchrysoeriol | 4'-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC50 of 19 nM for human P450 1B1-dependent EROD. |
| M44695 | 2',5,6',7-Tetrahydroxyflavone | 5,7,2',6'-Tetrahydroxyflavone is a natural flavonoid that inhibits hepatic testosterone 6β-hydroxylation (CYP3A4) activity with an IC50 of 7.8 μM. |
| M42318 | ONT-993 | ONT-993 is an aliphatic hydroxylated metabolite. |
| M42317 | CAY 10434 | CAY 10434 is a potent CYP4A hydroxylase inhibitor. |
| M42316 | Erysolin | Erysolin is a CYP1A inhibitor with antigenic toxicity. |
| M42315 | hCYP3A4-IN-1 | hCYP3A4-IN-1 is a potent, orally active hCYP3A4 inhibitor. |
| M42314 | SU 10603 | SU 10603 is a specific inhibitor of P45017α (P450c17; CYP17A1). |
| M42313 | CAY 10462 dihydrochloride | CAY 10434 dihydrochloride is a potent CYP4A hydroxylase inhibitor. |
| M42312 | CYP11A1-IN-1 | CYP11A1-IN-1 is an inhibitor of CYP11A1, with IC50 value of 201-2000 nM. |
| M42310 | hCYP3A4 Fluorogenic substrate 1 | hCYP3A4 Fluorogenic substrate 1 is a potrnt hCYP3A4 fluorogenic substrate with an Km value of 0.36 μM. |
| M42309 | hCYP1B1-IN-1 | hCYP1B1-IN-1 is a hCYP1B1 inhibitor (IC50=3.6 nM), as well as an antagonist of Aryl Hydrocarbon Receptor. |
| M39062 | Kushenol M | Kushenol M is a flavonoid from Sophora flavescens. Kushenol M is a cytochrome P450 (CYP) inhibitor, with IC50 values of 1.29 μM for CYP3A4 in human liver microsomes. |
| M39059 | Isoglycycoumarin | Isoglycycoumarin is a flavonoid isolated from the roots of Glycyrrhiza uralensis. Isoglycycoumarin is a highly selective probe for human cytochrome P450 2A6 (CYP2A6). |
| M39058 | Licopyranocoumarin | Licopyranocoumarin is an isoflavonoid that shows CYP3A4 inhibitory activity with an IC50 of 32 μM. Licopyranocoumarin has potent neuroprotective activities. |
| M39057 | 7-Hydroxyflavanone | 7-Hydroxyflavanone is a potent inhibitor of aromatase (CYP19) activity with the IC50 of 65 μM. 7-Hydroxyflavanone exerts various biological effects, including anticarcinogenic, antioxidant and (anti-)estrogenic effects, and modula |
| M39055 | 7-Ethoxy-4-methylcoumarin | 7-Ethoxy-4-methylcoumarin is a coumarin derivative and can be used as a substrate probe of mammalian cytochromes P450 1A1, 2B4 and 2B6. |
| M30622 | Dihydrolanosterol | Dihydrolanosterol is a subtrate of CYP51 and a cholesterol biosynthesis inhibitor.. |
| M30308 | 7-Ethoxyresorufin | 7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase. |
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