| Cat.No. | Name | Information |
|---|---|---|
| M2497 | Cathepsin Inhibitor 1 | Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively. |
| M9353 | N-Ethylmaleimide | N-Ethylmaleimide (NEM) is a cysteine protease inhibitor. |
| M3636 | Leupeptin hemisulfate | Leupeptin hemisulfate hemisulfate is the reversible inhibitor of lysosomal serine and cysteine proteinases; Leupeptin; inhibition of cathepsin B(Ki=6 nM), calpain(Ki=10 nM), trypsin (Ki=35 nM), plasmin (Ki=3.4 μM) and kallikrein (Ki=19 μM) had no effect on chymotrypsin, elastase, renin, or pepsin. |
| M1985 | Odanacatib | Odanacatib (MK-0822) is a potent and reversible covalent inhibitor of CathepsinK (CatK) with an IC50 of 0.2 nM/1 nM for human/rabbit cathepsin B, L, and S and is highly selective. |
| M6236 | CA-074 Me | CA-074 Me is a membrane-permeable derivative of CA-074 and acts as an irreversible cathepsin B inhibitor. |
| M28042 | Petesicatib | Petesicatib is a cathepsin S inhibitor, used in research of immune diseases. |
| M27825 | KGP94 | KGP94 is a selective inhibitor of cathepsin L with an IC50 of 189 nM. KGP94 inhibits migration and invasion of metastatic carcinoma and shows low cytotoxicity (GI50=26.9 µM) against various human cell lines. |
| M14309 | Z-LVG-CHN2 | Z-LVG-CHN2 is a cell-permeable and irreversible inhibitor of cysteine proteinase. |
| M14304 | 3-Epiursolic Acid | 3-Epiursolic Acid is a triterpenoid isolated from Myrtaceae, acts as a competitive inhibitor of cathepsin L (ICIC50, 6.5 μM; Ki, 19.5 μM), with no obvious effect on cathepsin B. |
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