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Casein Kinase Casein kinase 1

Cat.No.  Name Information
M1861 Silmitasertib (CX-4945) CX-4945 (Silmitasertib) is a potent small molecule protein kinase inhibitor that selectively binds to and inhibits the enzyme casein kinase II (CK2).
M45283 BTX161 BTX161 is a Thalidomide analog and potent CKIα degrader.BTX161 mediates the degradation of CKIα better than Lenalidomide and activates the DNA damage response (DDR) and p53 while stabilizing the p53 antagonist MDM2 in human AML cells.
M45282 CKI-7 free base CKI-7 free base is a potent and ATP-competitive casein kinase 1 (CK1) inhibitor with an IC50 of 6 μM and a Ki of 8.5 μM. In addition, CKI-7 free base selectively inhibits Cdc7 kinase, SGK, S6K1 and MSK1.
M41417 CK2-IN-7 CK2-IN-7 is an inhibitor of casein kinase 2 (CK2).
M41416 SR-4133 SR-4133 is a potent and highly CK1ε selective inhibitor with an IC50 of 58 nM.
M41415 CK1-IN-2 CK1-IN-2 is a potent CK1 inhibitor with an IC50 values of 123, 19.8, 26.8, 74.3 nM for CK1a, CK1d, CK1e, p38a, respectively.
M30853 TMCB  TMCB is a selective, ATP-competitive CK2 (casein kinase II) inhibitor with distinct Ki values of 83 nM and 21 nM for the two different catalytic CK2 subunits α and α', respectively.
M30022 SRPIN803  SRPIN803 is a potent CK2 and SRPK1 dual inhibitor, with IC50s of 203 nM and 2.4 μM, respectively. SRPIN803 exhibits antiangiogenic activity. SRPIN803 can be used for the research of age-related macular degeneration.
M21993 Casein Kinase II Inhibitor IV Casein Kinase II Inhibitor IV is a potent ATP-competitive casein kinase II inhibitor with an IC50 of 9 nM.In addition, Casein Kinase II Inhibitor IV is an inducer of human keratinocyte (NHEK) differentiation.
M21150 TMX-4116 TMX-4116 is a casein kinase 1α (CK1α) degradation agent. tmx-4116 shows a preference for CK1α degradation in MOLT4, Jurkat and MM.1S cells with DC50 less than 200 nM. tmx-4116 can be used in the study of multiple myeloma.
M21033 CK1-IN-1 CK1-IN-1 (PUN51207, Compound 1C) is an inhibitor of casein kinase 1 (CK1) with IC50 of 15 nM, 16 nM and 73 nM for CK1δ, CK1ε and p38α MAPK, respectively.
M20880 Ellagic Acid hydrate Ellagic acid is a potent inhibitor of protein kinase CK2 with IC50s of 0.04, 2.9 and 3.5 μM for CK2, Lyn and PKA respectively. It shows potent antioxidant, anti-mutagenic and antidepressant properties.
M20361 WAY-301527 WAY-301527 is a Casein kinase 1d inhibitor.
M20333 WAY-304800-A WAY-304800-A is a Casein kinase 1δ inhibitor.
M20321 WAY-625135 WAY-625135 is a Casein kinase 1δ inhibitor.
M20320 WAY-646458 WAY-646458 is a Casein kinase 1d inhibitor.
M20279 WAY-658341 WAY-658341 is a Casein kinase 1d inhibitor.
M20267 WAY-650886 WAY-650886 is a Casein kinase 1δ inhibitor
M20266 WAY-650313 WAY-650313 is a Casein kinase 1δ inhibitor.
M20261 WAY-647636 WAY-647636 is a Casein kinase 1δ inhibitor
M20254 WAY-639932 WAY-639932 is a Casein kinase 1δ inhibitor.




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