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Carboxylesterase Carboxylesterase (CES)

Inhibitor

Cat.No.  Name Information
M16775 Nevadensin Nevadensin (Lysionotin) is a selective human carboxylesterase 1 (hCE1) inhibitor with an IC50 of 2.64 μM. Nevadensin is more selective for hCE1 than hCE2 (IC50 of 132.8 μM). Nevadensin can induce apoptosis and DNA damage in cancer cells.
M4480 Bakuchiol Bakuchiol is a phytoestrogens from psoralea seeds that have anti-tumor and other effects. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) and human carboxylesterase 2 (hCE2), with IC50 values values of 40.9 μM and 7.28 μM, respectively.




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