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Calcium Channel Calcium Channel

Cat.No.  Name Information
M3621 Ionomycin Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus.
M3807 Ionomycin (Calcium salt) Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus.
M7409 Thapsigargin Thapsigargin is an endoplasmic reticulum (ER) stress inducer, it is also an inhibitor of microsomal Ca2+-ATPase.
M5073 (R)-(+)-BAY K 8644 (R)-(+)-BAY K 8644 is a calcium channel inhibitor, inhibits Ba2+ currents (IBa) with IC50 of 975 nM.
M3424 Nifedipine Nifedipine (BAY-a-1040) is a potent vasodilator agent with calcium antagonistic action.
M14204 Verapamil Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor.
M2820 Lomerizine dihydrochloride Lomerizine dihydrochloride is a relatively new L- and T-type calcium channel blocker used in the treatment of migraine.
M2520 Cinepazide maleate Cinepazide maleate is a maleate salt form of cinepazide which is a vasodilator.
M2496 Catharanthine Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 μM
M2425 Azelnidipine Azelnidipine is a novel dihydropyridine derivative, a L-type calcium channel blocker, and an antihypertensive. Azelnidipine inhibits the intracellular calcium ion flow and lower blood pressure by selectively blocking L-type calcium channel on the membrane of vascular smooth muscle. Azelnidipine inhibits esophageal squamous cell carcinoma proliferation by targeting MEK1/2. Azelnidipine also has anti-inflammatory, antioxidant and neuroprotective effects.
M2248 Cilnidipine Cilnidipine is a dual L- and N-type calcium channel blocker that displays antihypertensive, sympatholytic and neuroprotective activity.
M1927 KB-R7943 mesylate KB-R7943 mesylate is a potent, selective inhibitor of the reverse mode of the Na+/Ca2+ exchanger (IC50 = 0.7 mM).
M59414 TPC2-A1-N TPC2-A1-N is a powerful and Ca2+-permeable agonist of two pore channel 2 (TPC2), which plays its role by mimicking the physiological actions of NAADP.
M59227 TTA-Q6 TTA-Q6 is a selective T-type Ca2+ channel antagonist, which can be used in the research of neurological disease.
M56458 TTA-A8  TTA-A8 is a short-acting T-type calcium channel antagonist with oral activity, exhibiting an IC50 value of 31.3 nM in the FLIPR depolarization assay.
M56457 MONIRO-1  MONIRO-1 is a T-type and N-type calcium channel blocker with IC50 values of 34, 3.3, 1.7 and 7.2 µM against hCav2.2, hCav3.1, hCav3.2 and hCav3.3, respectively.
M56456 Azumolene Azumolene (EU4093 free base), a Dantrolene analog, is a muscle relaxant.
M56455 Nexopamil  Nexopamil is a calcium antagonist of Ca2+ channel, 5HT2, 5HT1A, 5HT1C and dopamine D2 receptors.
M56454 Azumolene sodium Azumolene sodium (EU4093) is an analog of Dantrolene that inhibits malignant hyperthermia (MH) syndrome and intracellular Ca2+ homeostasis failure caused by Halothane/Succinylcholine.
M56453 2-Chloro-ATP sodium  2-Chloro-ATP sodium (2-Chloro ATP) is an adenine nucleotide and an analog of ATP.
M56452 ML218 hydrochloride  ML218 hydrochloride is a potent, selective and orally active T-type Ca2+ channels (Cav3.1, Cav3.2, Cav3.3) inhibitor with IC50s of 310 nM and 270 nM for Cav3.2 and Cav3.3, respectively.
M56451 YS 035 hydrochloride  YS 035 hydrochloride is a Ca2+ antagonist on cellular uptake and mitochondrial efflux of calcium ions.
M56450 Ca2+ channel agonist 1  Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2, with EC50s of 14.23 μM and 3.34 μM, respectively, and is used as a potential treatment for motor nerve terminal dysfunction.
M56449 D-myo-Inositol 1,4,5-trisphosphate tripotassium D-myo-Inositol 1,4,5-trisphosphate tripotassium, a second messenger, elicits Ca2+ mobilization.
M55649 Monatepil maleate Monatepil maleate (AJ-2615) is a potent and orally active Ca2+-channel antagonist and a noncompetitive ACAT inhibitor. Monatepil maleate (AJ-2615) is also an α1-adrenoceptor antagonist.
M53706 ω-Agatoxin TK ω-Agatoxin TK, a peptidyl toxin of the venom of Agelenopsis aperta, is a potent and selective P/Q type Ca2+ channel blocker.




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