| Cat.No. | Name | Information |
|---|---|---|
| M3621 | Ionomycin | Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus. |
| M3807 | Ionomycin (Calcium salt) | Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus. |
| M7409 | Thapsigargin | Thapsigargin is an endoplasmic reticulum (ER) stress inducer, it is also an inhibitor of microsomal Ca2+-ATPase. |
| M5073 | (R)-(+)-BAY K 8644 | (R)-(+)-BAY K 8644 is a calcium channel inhibitor, inhibits Ba2+ currents (IBa) with IC50 of 975 nM. |
| M3424 | Nifedipine | Nifedipine (BAY-a-1040) is a potent vasodilator agent with calcium antagonistic action. |
| M14204 | Verapamil | Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. |
| M4349 | Catharanthine-hemitartrate | Catharanthine Tartrate is an alkaloid found in periwinces that inhibits voltage-gated L-type Ca2+ channels in a function-operated cell and has anti-tumor and blood pressure lowering activities. |
| M4089 | Ginsenoside-Ro | Ginsenoside Ro (Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V) has the antiplatelet effect of Ca2+ antagonist with IC50 of 155 μM. Ginsenoside Ro decreased TXA2 production and Ginsenoside Ro also slightly decreased COX-1 and TXAS activity. |
| M4076 | Ginsenoside-Rf | Ginsenoside Rf is a trace component of ginseng root. Ginsenoside Rf inhibits N-type Ca2+ channels. |
| M3959 | Felodipine | Felodipine is a L-type Ca2+ channel blocker that is selective over N-, R-, P/Q- and T-type channels with IC50 of 0.15 nM. |
| M3958 | Clevidipine butyrate | Clevidipine butyrate is an ultrashort-acting intravenous dihydropyridine calcium-channel blocker which is used as an agent for the reduction of blood pressure. |
| M3956 | Ranolazine dihydrochloride | Ranolazine (CVT 303) dihydrochloride is an anti-angina and anti-ischemia agent that works by inhibiting the late effects of inward sodium current (IC50 values of 6 μM and 12 μM for INa and IKr, respectively) without affecting heart rate or blood pressure. Ranolazine is also a partial inhibitor of fatty acid oxidation (FAO). |
| M3613 | NP118809 | NP-118809 (39-1B4) is a potent N-type calcium channel blockers (IC50= 0.11 uM) ; good selectivity over L-type calcium channels. |
| M3572 | Manidipine | Manidipine is a lipophilic, third-generation, highly vasoselective dihydropyridine calcium antagonist with an IC50 of 2.6 nM. |
| M3500 | Diltiazem hydrochloride | Diltiazem hydrochloride is a calcium channel blocker that inhibits the transmembrane influx of extracellular calcium ions. Diltiazem hydrochloride is used in studies related to tumor and cardiovascular diseases. |
| M3498 | Nimodipine | Nimodipine is an orally active, well-tolerated and light-sensitive dihydropyridine calcium antagonist and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity.Nimodipine decreases intracellular free Ca2+,Beclin-1 and autophagy. |
| M3462 | Nisoldipine | Nisoldipine (Sular) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM. |
| M3455 | Nitrendipine | Nitrendipine is a dihydropyridine calcium channel blocker with an IC50 of 95 nM. |
| M3440 | Nilvadipine | Nilvadipine is a potent calcium channel blocker with an IC50 of 0.03 nM. |
| M3365 | Tetracaine hydrochloride | Tetracaine hydrochloride is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor. |
| M3345 | Primidone | Primidone is an anticonvulsant of the pyrimidinedione class. Primidone is a neuronal voltage-gated sodium channel (VGSC) blocker and can be used for the study of epilepsy, essential tremor, and Psychiatric disorders. |
| M3296 | Manidipine dihydrochloride | Manidipine dihydrochloride is a hydrochloride salt form of Manidipine, which is a calcium channel blocker with IC50 of 2.6 nM, used clinically as an antihypertensive. Phase 4. |
| M3210 | Benidipine hydrochloride | Benidipine hydrochloride is a hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker. |
| M3118 | Verapamil hydrochloride | Verapamil hydrochloride (VPH) is an orally active L-type calcium channel inhibitor that eliminates calcium channel agonist-induced calcium inward flow and apoptosis. Verapamil hydrochloride is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. |
| M2921 | Penfluridol | Penfluridol (R-16341) effectively inhibits TNFα-induced NF-κB activation and alleviates the severity of arthritis and colitis in vivo. Penfluridol is a Ca2+-calmodulin inhibitor. Penfluridol induces apoptosis and autophagy. |
| M2881 | Nicardipine hydrochloride | Nicardipine is a dihydropyridine calcium-channel blocking agent used for the treatment of vascular disorders. |
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