| Cat.No. | Name | Information |
|---|---|---|
| M3621 | Ionomycin | Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus. |
| M3807 | Ionomycin (Calcium salt) | Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus. |
| M7409 | Thapsigargin | Thapsigargin is an endoplasmic reticulum (ER) stress inducer, it is also an inhibitor of microsomal Ca2+-ATPase. |
| M5073 | (R)-(+)-BAY K 8644 | (R)-(+)-BAY K 8644 is a calcium channel inhibitor, inhibits Ba2+ currents (IBa) with IC50 of 975 nM. |
| M3424 | Nifedipine | Nifedipine (BAY-a-1040) is a potent vasodilator agent with calcium antagonistic action. |
| M14204 | Verapamil | Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. |
| M14188 | ABT-639 | ABT-639 is a novel, peripherally acting, selective T-type Ca2+ channel blocker. |
| M14187 | ω-Conotoxin GVIA TFA | ω-Conotoxin GVIA TFA is an inhibitor of the N-type Ca2+ channel. |
| M11507 | Taurolithocholic acid sodium salt | Taurolithocholic acid sodium salt is an effective bile suppressor and Ca2+ agonist. |
| M11316 | Urolithin C | Urolithin C, a polyphenol intestinal microbial metabolite of ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is an L-type Ca2+ channel opening agent that enhances Ca2+ influx. Urolithin C induces apoptosis and stimulates the formation of reactive oxygen species (ROS) through mitochondria mediated pathway. |
| M10367 | Ruthenium red | Ruthenium red (Ammoniated ruthenium oxychloride) is a polycationic dye widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria. Ruthenium red is also a L-type calcium current (ICa) blocker, blocks Ca2+ uptake and release, and voltage-sensitive Ca2+ channels. |
| M9794 | Ebselen | Ebselen (SPI-1005) is a potent voltage-dependent calcium channel (VDCC) blocker. Ebselen is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen can permeate the blood-brain barrier and has anti-inflammatory, antioxidant and anticancer activity |
| M9720 | Aranidipine | Aranidipine (MPC1304) is a calcium channel blocker which may positively affect ambulatory blood pressure. *This compound is unstable in solutions, freshly prepared is recommended. |
| M9600 | 2-Aminoethyl diphenylborinate | 2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of IP3R, and regulate IP3-induced calcium release. 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca2+ (SOC) channel and activates some TRP channels (V1, V2 and V3). |
| M8859 | Xestospongin C | Xestospongin C is a selective, reversible and membrane-permeable inhibitor of IP3 receptor. |
| M8747 | Synta66 | Synta66 (S66) is a CRAC (Ca2+ release-activated Ca2+) channel inhibitor that blocks SOCE (store-operated Ca2+ entry) upon Ca2+ depletion from intracellular stores by thapsigargin in human vascular smooth muscle cells (VSMCs) with high potency (IC50 = 26 nM & 43 nM based on maximum Ca2+ level & rate of increase, respectly). |
| M8330 | Carboxyamidotriazole | Carboxyamidotriazole (L-651582) is an orally active calcium channel blocker. |
| M7993 | Palmitoylglycine | PalGly is an endogenous signaling lipid that modulates calcium influx and nitric oxide production. |
| M7778 | Dantrolene sodium salt | Dantrolene sodium is an orally active, non-competitive glutathione reductase inhibitor with a Ki of 111.6 μM and an IC50 of 52.3 μM. Dantrolene sodium is also a calcium channel protein inhibitor. Dantrolene sodium inhibits the release of Ca2+ from RyR1 and RyR3, which can be beneficial in a variety of pathologies caused by disruptions in calcium homeostasis. |
| M7106 | PD 173212 | PD 173212 is a potent N-type voltage-gated calcium channel blocker (IC50 = 36 nM). |
| M7034 | NNC 55-0396 dihydrochloride | NNC 55-0396 dihydrochloride is a highly selective Ca 2+ channel blocker (T-type). |
| M6499 | Bepridil hydrochloride | Bepridil hydrochloride (CERM 1978) is a calcium channel blocker, with antianginal activity. |
| M6185 | YM-58483 | YM-58483 is the first selective and potent inhibitor of CRAC channels and subsequent Ca2+ signals. |
| M6124 | Wilforgine | TwMDR1 transports sesquiterpene pyridine alkaloids, wilforine and wilforgine, into the hairy roots of T. wilfordii Hook.f. resulting in low secretion ratio of alkaloids. |
| M6092 | Mirogabalin | Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium-channel complexes in the CNS. |
| M6038 | Trimethadione | Trimethadione is an oxazolidinedione anticonvulsant; commonly used to treat epileptic conditions. |
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