| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M9075 | Etomoxir sodium salt | Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig. |
| M10320 | Chondroitin sulfate | Chondroitin sulfate is a class of sulfated glycosaminoglycans that are linear polysaccharides consisting of repeating disaccharide units composed of uronic acid and N-acetylhexosamine, which has been widely used in the treatment of osteoarthritis. |
| M10566 | Valepotriate | Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones. |
| M7755 | Dehydroleucodine | Dehydroleucodine is a sesquiterpene lactone isolated from Artemisia douglasiana Besser; mast cell stabilizers. |
| M38844 | Glyphosate | Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants. |
| M4375 | Hypericin | Hypericin is an extract of Hypericum perforatum, which has strong antiviral effect and anti-tumor effect. |
| M16194 | Boldine | Boldine is an oral effective antioxidant, anti-inflammatory, antitumor agent, and can inhibit osteoclast formation. Boldine induces apoptosis of human bladder cancer cells by regulating ERK, AKT and GSK-3β. Boldine ameliorates bone destruction by down-regulating the OPG/RANKL/RANK signaling pathway. It can be used in rheumatoid arthritis research. |
| M13519 | Rhapontin | Rhapontin (Rhaponiticin), a component of rhubarb (Rheum officinale Baillon), induces apoptosis resulting in suppression of proliferation of human stomach cancer KATO III cells. |
| M58126 | Deferoxamine | Deferoxamine (Deferoxamine B) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine upregulates HIF-1α levels with good antioxidant activity. Deferoxamine also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. |
| M7419 | Toyocamycin | Toyocamycin (Vengicide) is an adenosine analog produced by Streptomyces diastatochromogenes, acts as an XBP1 inhibitor. Toyocamycin blocks RNA synthesis and ribosome function, and induces apoptosis. Toyocamycin is a adenosine analog; antifungal antibiotic. |
| M7341 | Swainsonine | Swainsonine is a potent inhibitor of α-mannosidase II. Swainsonine induces apoptosis and cell cycle arrest at G2/M phase. |
| M7145 | Pladienolide B | Pladienolide B is a potent pre-mRNA splicing inhibitor, exerts antitumor activities mediated through the inhibition of pre-mRNA splicing. Pladienolide B is a potent cancer cell growth inhibitor that targets the SF3B1 subunit of the spliceosome. Pladienolide B induces apoptosis. |
| M6673 | DIM-C-pPhOH | DIM-C-pPhOH (C-DIM8, CDIM8) is a nur77 antagonist. DIM-C-pPhOH reduces cell proliferation with IC50 values of 13.6 μM and 13.0 μM for ACHN cells and 786-O cells, respectively. |
| M6567 | CCCP | CCCP is a oxidative phosphorylation uncoupler. CCCP induces activation of PINK1 leading to Parkin Ser65 phosphorylation. |
| M6553 | C16 | C16 is a pKR inhibitor. |
| M6313 | PTC-028 | PTC-028 is an orally bioavailable inhibitor of stem cell factor BMI-1, it downregulates BMI-1, inducing caspase-mediated apoptosis. PTC-028 is an orally bioavailable compound that decreases BMI-1 levels by posttranslational modification. |
| M6290 | Puromycin aminonucleoside | Puromycin aminonucleoside (PAN), which is an analogue of puromycin antibiotic, has been largely adopted to experimentally induce MCD in rodents (with a single high dose) or FSGS (by repeated doses for over a longer period). |
| M6257 | ONC212 | The ClpP activator ONC‐212 (TR‐31), a fluorinated-ONC201 analogue, is broadly efficacious across most solid tumors and hematological malignancies in the low nanomolar range and has robust anti-leukemic activity. |
| M5934 | Risedronate sodium | Risedronic acid (Risedronate) sodium, a bisphosphonate, is a potent anti-resorption agent that inhibits osteoclast-mediated bone resorption and changes the bone metabolism. Risedronic acid sodium suppresses osteoblast differentiation and induced caspase- and isoprenoid depletion-dependent apoptosis. |
| M5843 | Oxybenzone | Oxybenzone (Benzophenone 3) is a benzophenone derivative acts as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells. |
| M5761 | Mangafodipir trisodium | Mangafodipir is a contrast agent delivered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver. |
| M5689 | Hesperidin | Hesperidin (HP) is a bioflavonoid that plays a role in plant defense and is abundant in citrus species, such as grapefruit, lemon and orange. Hesperidin is used effectively as a supplemental agent in complementary therapy protocols. |
| M5636 | Etretinate | Etretinate is an orally available aromatic retinoid that has been shown to be effective in studies of cow skin and other skin syndromes. It can activate retinoid receptor, induce cell differentiation, inhibit cell proliferation and inhibit tissue infiltration. |
| M5623 | Escin | Escin is a mixture of saponins with anti-inflammatory, vasoconstrictor and vasoprotective effects found in Aesculus hippocastanum(the horse chestnut). |
| M5568 | Diatrizoic acid | Diatrizoic Acid is an organic, iodinated radiocontrast agent used in diagnostic radiography. |
| M5298 | NSC-144303 | Ubiquitin Isopeptidase Inhibitor I, G5 (NSC-144303) is a broad-spectrum cell-permeable deubiquitinating enzyme (DUB) inhibitor that affects type I IFNs and NF-κB induced by poly(I:C).*The compound is unstable in solutions, freshly prepared is recommended |
| M5191 | C-DIM12 | C-DIM12 is Nurr1 activator that stimulates Nurr1 mediated apoptosis axis in bladder cancer cells and tumors and inhibits NF-κB–dependent gene expression in glial cells. |
| M5173 | 8-Prenylnaringenin | 8-Prenylnaringenin is a prenylflavonoid isolated from hop cones Humulus lupulus, with cytotoxicity. 8-prenylnaringenin has anti-proliferative activity against HCT-116 colon cancer cells via induction of intrinsic and extrinsic pathway-mediated apoptosis. |
| M4971 | Azoramide | Azoramide is a potent, orally active small-molecule modulator of the unfolded protein response (UPR). Azoramide is a small-molecule modulator of the unfolded protein response with antidiabetic activity. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
