| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M9075 | Etomoxir sodium salt | Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig. |
| M10320 | Chondroitin sulfate | Chondroitin sulfate is a class of sulfated glycosaminoglycans that are linear polysaccharides consisting of repeating disaccharide units composed of uronic acid and N-acetylhexosamine, which has been widely used in the treatment of osteoarthritis. |
| M10566 | Valepotriate | Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones. |
| M7755 | Dehydroleucodine | Dehydroleucodine is a sesquiterpene lactone isolated from Artemisia douglasiana Besser; mast cell stabilizers. |
| M38844 | Glyphosate | Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants. |
| M4375 | Hypericin | Hypericin is an extract of Hypericum perforatum, which has strong antiviral effect and anti-tumor effect. |
| M16194 | Boldine | Boldine is an oral effective antioxidant, anti-inflammatory, antitumor agent, and can inhibit osteoclast formation. Boldine induces apoptosis of human bladder cancer cells by regulating ERK, AKT and GSK-3β. Boldine ameliorates bone destruction by down-regulating the OPG/RANKL/RANK signaling pathway. It can be used in rheumatoid arthritis research. |
| M13519 | Rhapontin | Rhapontin (Rhaponiticin), a component of rhubarb (Rheum officinale Baillon), induces apoptosis resulting in suppression of proliferation of human stomach cancer KATO III cells. |
| M58126 | Deferoxamine | Deferoxamine (Deferoxamine B) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine upregulates HIF-1α levels with good antioxidant activity. Deferoxamine also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. |
| M18292 | 4-Hydroxybenzyl alcohol | 4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants, with anti-inflammatory, anti-oxidant, anti-nociceptive activity. |
| M18267 | 3-O-Acetyloleanolic acid | 3-O-Acetyloleanolic acid |
| M18178 | 3-oxo-urs-12-en-28-oic acid | 3-oxo-urs-12-en-28-oic acid |
| M17797 | Quillaic acid | Quillaic acid is an anti-gastric cancer and anti-proliferation agent that can promote apoptosis of cancer cells. Quillaic acid also has analgesic and local anti-inflammatory activity. |
| M16932 | (+)-Pinoresinol | (+)-Pinoresinol is a lignol which drastically sensitizes cancer cells against TNF-related apoptosis-inducing ligand (TRAIL) -induced apoptosis. |
| M16778 | Gardenin B | Gardenin B is a flavonoid isolated from Gardenia jasminoides. Gardenin B induces cell death in human leukemia cells involves multiple caspases. |
| M16777 | Salvigenin | Salvigenin is a natural polyphenolic compound, with neuroprotective effect. Salvigenin has antitumor cytotoxic and immunomodulatory properties. Salvigenin inhibits H2O2-induced cell apoptosis. |
| M16760 | Kumatakenin | Kumatakenin is a flavonoid isolated from cloves, which shows the effect of inducing apoptosis in ovarian cancer cells. |
| M16672 | Sophoraflavanone G | Sophoraflavanone G induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways. Sophoraflavanone G (Kushenol F) shows anti-tumor and anti-inflammatory properties. |
| M16525 | Pinusolide | Pinusolide is a known platelet-activating factor (PAF) receptor binding antagonist. Pinusolide not only decreases the proliferation activity of tumor cells but specifically induces apoptosis. |
| M15094 | Bromelain | Bromelain, an anti-inflammatory compound derived from pineapple stem, acts by down-regulating plasma kinkinin, inhibiting prostaglandin E2 expression, degradation of receptors for advanced glycation end products, regulation of angiogenic biomarkers, and antioxidant activity upstream of the COX pathway. Can be used as a food additive. |
| M14658 | Barbadin | Barbadin is a novel and selective β-arrestin/β2-adaptin interaction inhibitor, has IC50 values of 19.1 μM for β-arrestin1 and 15.6 μM for β-arrestin2. |
| M13522 | Sophoridine | Sophoridine is a quinolizidine alkaloid isolated from leafs of Leguminous plant Sophora alopecuroides.L. |
| M13520 | Ro 08-2750 | Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC50 of ~ 1 µM. |
| M13518 | Poncirin | Poncirin is isolated from Poncirus trifoliata with anti-inflammory activites. Poncirin significantly reduces mechanical hyperalgesia and allodynia in Complete Freund’s Adjuvant (CFA)-induced inflammatory pain models. |
| M13514 | Neobavaisoflavone | Neobavaisoflavone, a flavonoid, is isolated from the seeds of Psoralea corylifolia. |
| M13513 | Naphthazarin | Naphthazarin (DHNQ) is a naturally occurring compound. |
| M13511 | Iberin | Iberin (NSC 321801), a sulfoxide analogue of sulforaphane, is a naturally occurring member of isothiocyanate family. Iberin inhibits cell survival with an IC50 of 2.3 μM in HL60 cell. Iberin induces apoptosis. |
| M13510 | Hematoporphyrin dihydrochloride | Hematoporphyrin dihydrochloride (Hematoporphyrin IX dihydrochloride), a photosensitizer, is a substrate for affinity chromatography of heme-binding proteins. |
| M13509 | GPNA hydrochloride | GPNA hydrochloride is a well known substrate of the enzyme γ-glutamyltransferase (GGT). |
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