| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M9075 | Etomoxir sodium salt | Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig. |
| M10320 | Chondroitin sulfate | Chondroitin sulfate is a class of sulfated glycosaminoglycans that are linear polysaccharides consisting of repeating disaccharide units composed of uronic acid and N-acetylhexosamine, which has been widely used in the treatment of osteoarthritis. |
| M10566 | Valepotriate | Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones. |
| M7755 | Dehydroleucodine | Dehydroleucodine is a sesquiterpene lactone isolated from Artemisia douglasiana Besser; mast cell stabilizers. |
| M38844 | Glyphosate | Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants. |
| M4375 | Hypericin | Hypericin is an extract of Hypericum perforatum, which has strong antiviral effect and anti-tumor effect. |
| M16194 | Boldine | Boldine is an oral effective antioxidant, anti-inflammatory, antitumor agent, and can inhibit osteoclast formation. Boldine induces apoptosis of human bladder cancer cells by regulating ERK, AKT and GSK-3β. Boldine ameliorates bone destruction by down-regulating the OPG/RANKL/RANK signaling pathway. It can be used in rheumatoid arthritis research. |
| M13519 | Rhapontin | Rhapontin (Rhaponiticin), a component of rhubarb (Rheum officinale Baillon), induces apoptosis resulting in suppression of proliferation of human stomach cancer KATO III cells. |
| M58126 | Deferoxamine | Deferoxamine (Deferoxamine B) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine upregulates HIF-1α levels with good antioxidant activity. Deferoxamine also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. |
| M41303 | Hydroxy-PP-Me | Hydroxy-PP-Me is a potent and specific CBR1 inhibitor with an IC50 of 759 nM. |
| M41302 | SLC7A11-IN-1 | SLC7A11-IN-1 is a potent solute carrier family 7 member 11 (SLC7A11, xCT) inhibitor. |
| M41301 | Vallesiachotamine | Vallesiachotamine, a known monoterpene indole alkaloid, possesses anti-tumor activity. |
| M41300 | CDK8-IN-13 | CDK8-IN-13 is a potent, selective and orally active CDK8 inhibitor with an IC50 value of 51.9 nM. |
| M41299 | Apoptosis inducer 12 | Apoptosis inducer 12 is an apoptosis inducer that induces apoptosis through the mitochondrial pathway. |
| M41298 | ASR-488 | ASR-488 activates the mRNA-binding protein CPEB1, induces apoptosis and inhibits bladder cancer growth. |
| M41297 | Antimycin A2c | Anticancer agent 141 is an antimycin alkaloid, with inhibitory pottential in HPV infected-cervical cancer. |
| M41296 | TAT-NEP1-40 acetate | TAT-NEP1-40 acetate is a therapeutic candidate for axonal regeneration and functional recovery after stroke. |
| M41295 | GSPT1 degrader-1 | GSPT1 degrader-1 is a potent degrader of G1 to S phase transition 1 (GSPT1) via ubiquitin-proteasome system. |
| M41294 | Ganoderic acid Mk | Ganoderic acid Mk (GA-Mk) is a triterpenoid acid, that can be isolated from the mycelia of Ganoderma lucidum. |
| M41293 | RUNX-IN-2 | RUNX-IN-2 covalently binds to the RUNX-binding sequences, and inhibits the binding of RUNX proteins to their target sites. |
| M41292 | RUNX-IN-1 | RUNX-IN-1 covalently binds to the RUNX-binding sequences, and inhibits the binding of RUNX proteins to their target sites. |
| M41290 | BRD0476 | BRD0476 is an inhibitor of pancreatic β-cell apoptosis with an EC50 value of 0.78 μM and a maximal inhibitory activity of 99%. |
| M41289 | Ganoderic acid S | Ganoderic acid S is a positional isomer of ganoderic acids, that can be isolated from the fermented mycelia of Ganoderma lucidum. |
| M41288 | EGFR-IN-78 | EGFR-IN-78, a 2-aminopyrimidine derivative, is a reversible inhibitor of EGFRC797S-TK, and also an inducer of apoptosis. |
| M41287 | Pyridinium bisretinoid A2E TFA | Pyridinium bisretinoid A2E (A2E) TFA is a fluorophore that can be isolated from lipofuscin in the retinal pigment epithelium (RPE). |
| M41286 | Euptox A | Euptox A (9-Oxo-10, 11-dehydroageraphorone), a cadenine sesquiterpene, is the main toxin that can be isolated from Eupatorium adenophorum. |
| M41285 | CPT2 | CPT2 (Carnitine palmitoyltransferase 2), an enzyme that participates in fatty acid oxidation, also is a colorectal cancer (CRC) prognostic biomarker. |
| M41284 | d-Sophoridine | d-Sophoridine ((+)-Sophoridine) is the dextro isoform of Sophoridine, which is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. |
| M41283 | Yakuchinone A | Yakuchinone A is a natural product isolated from the fruit of Alpinia oxyphylla, which can induce apoptosis and has anticancer and anti-inflammatory activities. |
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