| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M9075 | Etomoxir sodium salt | Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig. |
| M10320 | Chondroitin sulfate | Chondroitin sulfate is a class of sulfated glycosaminoglycans that are linear polysaccharides consisting of repeating disaccharide units composed of uronic acid and N-acetylhexosamine, which has been widely used in the treatment of osteoarthritis. |
| M10566 | Valepotriate | Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones. |
| M7755 | Dehydroleucodine | Dehydroleucodine is a sesquiterpene lactone isolated from Artemisia douglasiana Besser; mast cell stabilizers. |
| M38844 | Glyphosate | Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants. |
| M4375 | Hypericin | Hypericin is an extract of Hypericum perforatum, which has strong antiviral effect and anti-tumor effect. |
| M16194 | Boldine | Boldine is an oral effective antioxidant, anti-inflammatory, antitumor agent, and can inhibit osteoclast formation. Boldine induces apoptosis of human bladder cancer cells by regulating ERK, AKT and GSK-3β. Boldine ameliorates bone destruction by down-regulating the OPG/RANKL/RANK signaling pathway. It can be used in rheumatoid arthritis research. |
| M13519 | Rhapontin | Rhapontin (Rhaponiticin), a component of rhubarb (Rheum officinale Baillon), induces apoptosis resulting in suppression of proliferation of human stomach cancer KATO III cells. |
| M58126 | Deferoxamine | Deferoxamine (Deferoxamine B) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine upregulates HIF-1α levels with good antioxidant activity. Deferoxamine also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. |
| M49502 | C24:1-Ceramide | C24:1-Ceramide is one of the most abundant naturally occurring ceramide. |
| M49483 | B-355252 | B-355252 is a phenoxythiophene sulfonamide small molecule and a potent NGF receptor agonist that enhances NGF-induced neurite growth. It also protects ischemic neurons from neuronal loss by attenuating DNA damage, reducing ROS production and LDH levels, and preventing neuronal apoptosis. In addition, B355252 has anti-apoptotic effects in glutamate-induced excitotoxicity and in a mouse hippocampal cell line (HT22) model of Parkinson's disease (PD). |
| M44980 | Picrasidine Q | Picrasidine Q, an alkaloid component extracted from Angelica keiskei species, has the capacity of anti-cell transformation and anti-cancer. |
| M44924 | Malvidin-3-O-galactoside chloride | Malvidin-3-galactoside chloride, an anthocyanin monomer, induces hepatocellular carcinoma (HCC) cells cycle arrest and apoptosis. |
| M44795 | Biatractylolide | Biatractylolide is a compound isolated from the ethyl acetate extract of Atractylodes macrocephala. |
| M44780 | Apioline | Apiole is an anti-tumor agent that induces apoptosis and inhibits human colon cancer cells by inducing G0/G1 cell cycle arrest. |
| M44673 | (E)-[6]-Dehydroparadol | (E)-[6]-Dehydroparadol, an oxidative metabolite of [6]-Shogaol (HY-14616), is a potent Nrf2 activator. (E)-[6]-Dehydroparadol can inhibit the growth and induce the apoptosis of human cancer cells. |
| M43377 | PI3Kδ-IN-16 | PI3Kδ-IN-16 is a potent and selective inhibitor of PI3Kδ. |
| M43376 | FD2157 | FD2157 is a photosensitive PI3K inhibitor, with IC50s of 43 nM, 83 nM, 84 nM, 14 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ respectively. |
| M41359 | KWCN-41 | KWCN-41 is a selective and efficient inhibitor of RIPK1 kinase with an IC50 value of 88 nM. |
| M41313 | Angophorol | Angophorol is a flavonone compound. |
| M41312 | Zalypsis | Zalypsis (PM00104) has anti-tumor activity. |
| M41311 | RTA 744 | RTA 744 (WP 744) is a Doxorubicin analogue. |
| M41310 | Ganoderic acid R | Ganoderic acid R is a potent anticancer agent. |
| M41309 | Ganoderic acid Mf | Ganoderic acid Mf is an antitumor triterpenoid. |
| M41308 | Secalonic acid D | Secalonic acid D is isolated from the metabolites of Aspergillus aculeatus. Secalonic acid D activates GSK3-β, and degrades β-catenin. |
| M41307 | Ganoderic acid T1 | Ganoderic acid T1 is a deacetylated derivative of Ganoderic acid T. |
| M41306 | Ara-SH | Ara-SH is a Cytarabine mercaptopropionic acid-substituted derivative. |
| M41305 | Tubulin inhibitor 32 | Tubulin inhibitor 32 is a potent and orally active tubulin inhibitor. |
| M41304 | Apoptosis inducer 11 | Apoptosis inducer 11 induces apoptosis through the mitochondrial pathway. |
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