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Apoptosis Apoptosis related

Cat.No.  Name Information
M2206 TH-302 (Evofosfamide) TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM.
M9075 Etomoxir sodium salt Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig.
M10320 Chondroitin sulfate Chondroitin sulfate is a class of sulfated glycosaminoglycans that are linear polysaccharides consisting of repeating disaccharide units composed of uronic acid and N-acetylhexosamine, which has been widely used in the treatment of osteoarthritis.
M10566 Valepotriate Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones.
M7755 Dehydroleucodine Dehydroleucodine is a sesquiterpene lactone isolated from Artemisia douglasiana Besser; mast cell stabilizers.
M38844 Glyphosate Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants.
M4375 Hypericin Hypericin is an extract of Hypericum perforatum, which has strong antiviral effect and anti-tumor effect.
M16194 Boldine Boldine is an oral effective antioxidant, anti-inflammatory, antitumor agent, and can inhibit osteoclast formation. Boldine induces apoptosis of human bladder cancer cells by regulating ERK, AKT and GSK-3β. Boldine ameliorates bone destruction by down-regulating the OPG/RANKL/RANK signaling pathway. It can be used in rheumatoid arthritis research.
M13519 Rhapontin Rhapontin (Rhaponiticin), a component of rhubarb (Rheum officinale Baillon), induces apoptosis resulting in suppression of proliferation of human stomach cancer KATO III cells.
M58126 Deferoxamine Deferoxamine (Deferoxamine B) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine upregulates HIF-1α levels with good antioxidant activity. Deferoxamine also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells.
M53428 NTR 368 NTR 368 is a peptide derived from p75 neurotrophin receptor (p75NTR) corresponding to residues 368-381 of the human receptor.
M53427 (Gly14)-Humanin (human) (Gly14)-Humanin (human) (14-Glycine-Humanin (human)) is an analog of Humanin in which the 14th amino acid serine was replaced with glycine (Gly).
M53426 Tumor targeted pro-apoptotic peptide Tumor targeted pro-apoptotic peptide (CNGRC-GG-D(KLAKLAK)2) is an anti-tumor peptide.
M53425 Argipressin diacetate Argipressin (diacetate) (AVP (diacetate), also known as antidiuretic hormone (ADH)) is a 9 amino acid neuropeptide secreted by the posterior pituitary.
M53424 WLSEAGPVVTVRALRGTGSW WLSEAGPVVTVRALRGTGSW is a cardiomyocyte specific peptide.
M53423 Ac-IETD-CHO Ac-IETD-CHO is a potent, reversible inhibitor of granzyme B and caspase-8.
M53422 Amyloid 17-42 Amyloid 17-42 (Aβ(17-42)) is a major constituent of diffuse plaques in Alzheimer's disease and cerebellar pre-amyloid in Down's syndrome, derived by alpha- and gamma-secretase cleavage of the amyloid precursor protein (APP).
M53421 Malformin A1 Malformin A1, a cyclic pentapeptide isolated from Aspergillus niger, possess a range of bioactive properties including antibacterial activity.
M53420 Fexapotide Fexapotide (NX-1207 free acid) induces apoptosis selectively, reducing prostate volume at a cellular level.
M53419 Tigapotide Tigapotide (PCK-3145) is an anti-tumour peptide that reduces the development of skeletal metastases associated with prostate cancer.
M53418 cpm-1285 cpm-1285 induces apoptosis by functionally blocking intracellular Bcl-2 and related death antagonists.
M53417 ABT-510 ABT-510 is an anti-angiogenic TSP peptide (Thrombospondin-1 analogue) that induces apoptosis and inhibits ovarian tumour growth in an orthotopic, syngeneic model of epithelial ovarian cancer.
M53416 HKPao HKPao (Hunter-killer peptide ao) is a biologically active peptide.
M53415 Kp7-6 Kp7-6, a Fas mimetic peptide, is a Fas/FasL antagonist.
M53414 HXR9 HXR9 is a cell-permeable peptide and a competitive antagonist of HOX/PBX interaction.
M52819 c-JUN peptide c-JUN peptide is a cell-permeable c-JUN-JNK interaction inhibitor.
M49844 6-Formylpterin  6-Formylpterin is an inhibitor of Xanthine Oxidase. 6-Formylpterin induces intracellular ROS generation and apoptosis in HL-60 cells. 6-Formylpterin suppresses cell proliferation in PanC-1 cells.
M49505 STAT3-IN-9 STAT3-IN-9 is a potent STAT3 inhibitor.
M49504 JAK-2/3-IN-3 JAK-2-/3-IN-3 is a potent JAK2/3 inhibitor with IC50s of 13.00 and 14.86 nM for JAK2 and JAK3, respectively.
M49503 Bozepinib Bozepinib is a PKR (RNA-dependent protein kinase) activator and potently inhibits the HER-2 signaling pathway as well as JNK and ERK kinases.




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