| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M9075 | Etomoxir sodium salt | Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig. |
| M10320 | Chondroitin sulfate | Chondroitin sulfate is a class of sulfated glycosaminoglycans that are linear polysaccharides consisting of repeating disaccharide units composed of uronic acid and N-acetylhexosamine, which has been widely used in the treatment of osteoarthritis. |
| M10566 | Valepotriate | Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones. |
| M7755 | Dehydroleucodine | Dehydroleucodine is a sesquiterpene lactone isolated from Artemisia douglasiana Besser; mast cell stabilizers. |
| M38844 | Glyphosate | Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants. |
| M4375 | Hypericin | Hypericin is an extract of Hypericum perforatum, which has strong antiviral effect and anti-tumor effect. |
| M16194 | Boldine | Boldine is an oral effective antioxidant, anti-inflammatory, antitumor agent, and can inhibit osteoclast formation. Boldine induces apoptosis of human bladder cancer cells by regulating ERK, AKT and GSK-3β. Boldine ameliorates bone destruction by down-regulating the OPG/RANKL/RANK signaling pathway. It can be used in rheumatoid arthritis research. |
| M13519 | Rhapontin | Rhapontin (Rhaponiticin), a component of rhubarb (Rheum officinale Baillon), induces apoptosis resulting in suppression of proliferation of human stomach cancer KATO III cells. |
| M58126 | Deferoxamine | Deferoxamine (Deferoxamine B) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine upregulates HIF-1α levels with good antioxidant activity. Deferoxamine also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. |
| M55874 | YM281 | YM281 is a potent EZH2 inhibitor. |
| M55873 | DB1976 | DB1976 is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. |
| M55870 | LYG-202 | LYG-202, a flavonoid, has potent anti-angiogenic and antitumor activity. |
| M55869 | nor-NOHA | nor-NOHA is a selective and reversible arginase inhibitor. |
| M55868 | Benidipine | Benidipine is a potent and orally active calcium channel antagonist. |
| M55867 | Oxythiamine | Oxythiamine (Hydroxythiamin), an analogue of anti-metabolite, can suppress the non-oxidative synthesis of ribose and induce cell apoptosis. |
| M55866 | Imifoplatin | Imifoplatin (PT-112) is a platinum-based agent belonging to the phosphaplatin family. |
| M55865 | Sparfosic acid | Sparfosic acid, a DNA antimetabolite agent, is a potent inhibitor of aspartate transcarbamoyl transferase, the enzyme catalyzing the second step of de novo pyrimidine biosynthesis. |
| M55864 | Flurochloridone | Flurochloridone (R-40244) is a selective preemergence and persistent herbicide. |
| M55863 | Ap4A tetraammonium | Ap4A tetraammonium (P1,P4-Di-(adenosine-5')-tetraphosphate tetraammonium) is a conserved second messenger in organisms ranging from bacteria to humans. |
| M55862 | Oxythiamine chloride | Oxythiamine (Hydroxythiamine) chloride, an analogue of anti-metabolite, can suppress the non-oxidative synthesis of ribose and induce cell apoptosis. |
| M55861 | DB1976 dihydrochloride | DB1976 dihydrochloride is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. |
| M55860 | 7,8-Dihydroneopterin | 7,8-Dihydroneopterin, an inflammation marker, induces cellular apoptosis in astrocytes and neurons via enhancement of nitric oxide synthase (iNOS) expression. |
| M55858 | BIBU1361 dihydrochloride | BIBU1361 dihydrochloride induces apoptosis and inhibits autophagy. |
| M55643 | SKLB-163 | SKLB-163 is an orally active inhibitor for Rho GDP-dissociation (RhoGDI). SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK. SKLB-163 inhibits highly expressed RhoGDI tumor cell proliferation and migration, and increases radiosensitivity of tumor cells. SKLB-163 induces cancer cell Apoptosis. |
| M54495 | GLP-2(rat) | GLP-2(rat) is an intestinal growth factor. |
| M54364 | Edratide | Edratide (TV 4710) is a synthetic peptide of 19 amino acid based on the complementarity-determining region 1 (CDR1) of a human anti-DNA antibody that expresses a major idiotype denoted 16/6 Id. |
| M54262 | Thrombospondin-1 (1016-1023) (human, bovine, mouse) | Thrombospondin-1 (1016-1023) (human, bovine, mouse), is the C-terminal end of the native sequence of Thrombospondin-1 (TSP-1), is a CD47 agonist peptide. |
| M54140 | ABT-510 acetate | ABT-510 acetate is an anti-angiogenic TSP peptide (Thrombospondin-1 analogue) that induces apoptosis and inhibits ovarian tumour growth in an orthotopic, syngeneic model of epithelial ovarian cancer. |
| M53429 | Bax BH3 peptide (55-74), wild type | Bax BH3 peptide (55-74), wild type is a 20-amino acid Bax BH3 peptide (Bax 1) capable of inducing apoptosis in a variety of cell line models. |
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