| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M9075 | Etomoxir sodium salt | Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig. |
| M10320 | Chondroitin sulfate | Chondroitin sulfate is a class of sulfated glycosaminoglycans that are linear polysaccharides consisting of repeating disaccharide units composed of uronic acid and N-acetylhexosamine, which has been widely used in the treatment of osteoarthritis. |
| M10566 | Valepotriate | Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones. |
| M7755 | Dehydroleucodine | Dehydroleucodine is a sesquiterpene lactone isolated from Artemisia douglasiana Besser; mast cell stabilizers. |
| M38844 | Glyphosate | Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants. |
| M4375 | Hypericin | Hypericin is an extract of Hypericum perforatum, which has strong antiviral effect and anti-tumor effect. |
| M16194 | Boldine | Boldine is an oral effective antioxidant, anti-inflammatory, antitumor agent, and can inhibit osteoclast formation. Boldine induces apoptosis of human bladder cancer cells by regulating ERK, AKT and GSK-3β. Boldine ameliorates bone destruction by down-regulating the OPG/RANKL/RANK signaling pathway. It can be used in rheumatoid arthritis research. |
| M13519 | Rhapontin | Rhapontin (Rhaponiticin), a component of rhubarb (Rheum officinale Baillon), induces apoptosis resulting in suppression of proliferation of human stomach cancer KATO III cells. |
| M58126 | Deferoxamine | Deferoxamine (Deferoxamine B) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine upregulates HIF-1α levels with good antioxidant activity. Deferoxamine also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. |
| M4198 | Demethylzeylasteral | Demethylzeylasteral is a triterpene compound isolated from Tripterygium wilfordii with anti-inflammatory, immunosuppressive and anti-tumor activities. Demethylzeylasteral significantly reduces atherosclerosis (AS). Demethylzeylasteral inhibits triple negative breast cancer by blocking TGF-β signaling pathway. |
| M4153 | Genistin | Genistin (Genistine) is a kind of isoflavone of phytoestrogens, which is an effective antiadipogenic agent. Genistin inhibits breast cancer cell growth and promotes apoptotic cell death by regulating ERalpha signaling pathway. |
| M4109 | Alisol-B-23-acetate | Alisol B 23-acetate (23-acetylalismol B) is a triterpenoid compound that promotes regeneration of damaged liver by activating farnesol receptors. |
| M4104 | 20(S)-NotoginsenosideR2 | Notoginsenoside R2(Notoginsenoside R2) is a newly isolated panax Notoginsenoside R2, which showed protective effects against oxidative stress and cell apoptosis induced by 6-OHDA. |
| M4087 | Ginsenoside-F5 | Ginsenoside F5, which was obtained from Panax ginseng, significantly inhibited the growth of HL-60 cells through apoptosis pathway. |
| M4086 | Ginsenoside-F4 | Ginsenoside F4 (GF4), Ginsenoside, isolated from Panax notoginseng or red ginseng. Ginsenoside F4 (GF4) can inhibit human lymphocytic tumor JK cells by inducing apoptosis. Ginsenoside F4 (GF4) inhibited the expression of matrix metalloproteinase 13 (MMP 13) in IL-1β -treated chondrocytes, blocked cartilage damage in rabbit cartilage tissue culture, and prevented cartilage collagen matrix decomposition in pathological tissues. |
| M4084 | Ginsenoside-F2 | Ginsenoside F2, a metabolite of Ginsenoside Rb1, induces apoptosis and protective autophagy in breast cancer stem cells. |
| M4046 | Calycosin | Calycosin is a natural compound that can be isolated from Radix Astragali., with antioxidant and anti-inflammatory activities. Calycosin can be used for the research of ovarian cancer and breast cancer. |
| M3967 | α-Hederin | α-Hederin is a triterpene saponin which affects the binding behavior, dynamics, and regulation of beta 2-adrenergic receptors. |
| M3943 | Sanguinarine | Sanguinarine, a plant alkaloid with anti-proliferative effects against cancers, is a potent and specific protein phosphatase (PP) 2C inhibitor. |
| M3425 | Mitotane | Mitotane is an isomer of DDD and a derivative of DDT that induces CYP3A4 gene expression through steroid and exogenous receptor (SXR) activation, and has anticancer activity, and may be used in studies related to adrenocortical carcinoma. |
| M3307 | 5-Aminolevulinic acid hydrochloride | 5-Aminolevulinic acid hydrochloride is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles. |
| M2763 | Ibandronate sodium | Ibandronate sodium is a potent nitrogen-containing bisphosphonate that can be used in studies related to osteoporosis. |
| M2557 | Ezatiostat | Ezatiostat (TER199, TLK199) is a glutathione analog inhibitor of glutathione S-transferase (GST) P1-1. Ezatiostat leads to JNK activation by inhibiting GSTP1. Ezatiostat stimulates both lymphocyte production and bone marrow progenitor proliferation. |
| M2375 | Aloperine | Aloperine is exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties. |
| M1955 | 23-Hydroxybetulinic acid | 23-Hydroxybetulinic acid is a novel anticancer substance. |
| M58358 | DB2115 tertahydrochloride | DB2115 tertahydrochloride is a potent inhibitor of myeloid master regulator PU.1. DB2115 tertahydrochloride has the potential for researching cancers, including hematologic cancers. |
| M58200 | 14-3-3η Protein inhibitor 1 | 14-3-3η Protein inhibitor 1 is a 14-3-3η protein inhibitor with a KD of 35 µM. |
| M55877 | SEC | SEC induces activation of ANXA7 GTPase via the AMPK/mTORC1/STAT3 signaling pathway. |
| M55876 | Ap4A | Ap4A (P1,P4-Di-(adenosine-5')-tetraphosphate) is a conserved second messenger in organisms ranging from bacteria to humans. |
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