| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M9075 | Etomoxir sodium salt | Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig. |
| M10320 | Chondroitin sulfate | Chondroitin sulfate is a class of sulfated glycosaminoglycans that are linear polysaccharides consisting of repeating disaccharide units composed of uronic acid and N-acetylhexosamine, which has been widely used in the treatment of osteoarthritis. |
| M10566 | Valepotriate | Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones. |
| M7755 | Dehydroleucodine | Dehydroleucodine is a sesquiterpene lactone isolated from Artemisia douglasiana Besser; mast cell stabilizers. |
| M38844 | Glyphosate | Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants. |
| M4375 | Hypericin | Hypericin is an extract of Hypericum perforatum, which has strong antiviral effect and anti-tumor effect. |
| M16194 | Boldine | Boldine is an oral effective antioxidant, anti-inflammatory, antitumor agent, and can inhibit osteoclast formation. Boldine induces apoptosis of human bladder cancer cells by regulating ERK, AKT and GSK-3β. Boldine ameliorates bone destruction by down-regulating the OPG/RANKL/RANK signaling pathway. It can be used in rheumatoid arthritis research. |
| M13519 | Rhapontin | Rhapontin (Rhaponiticin), a component of rhubarb (Rheum officinale Baillon), induces apoptosis resulting in suppression of proliferation of human stomach cancer KATO III cells. |
| M58126 | Deferoxamine | Deferoxamine (Deferoxamine B) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine upregulates HIF-1α levels with good antioxidant activity. Deferoxamine also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. |
| M4434 | Isoalantolactone | Isoalantolactone is an alkylating agent used as an apoptosis inducer. |
| M4432 | Columbianadin | Columbianadin is a natural coumarin from Angelica Decursiva (Umbelliferae) and is known to have a variety of biological activities, including anti-inflammatory and anticancer effects. |
| M4429 | Levistilide A | Levistilide A (Levistolide A) is a natural compound isolated from the traditional Chinese medicine Ligusticum chuanxiong and used to study cancer. Levistilide A (Levistolide A) induces apoptosis through ENDOplasmic reticulum stress mediated by ROS. |
| M4424 | Tetramethylpyrazine (2,3,5,6-Tetramethylpyrazine) | Tetramethylpyrazine (2,3,5,6-Tetramethylpyrazine) is an alkyl pyrazine extracted from Ligusticum wallichii (Chuan Xiong), often used as a flavor in French fries, bread, tea, dairy products, bean products and other food. Ligustrazine has potential antineural and anti-inflammatory activities in rats. |
| M4405 | Obacunone | Obacunone is isolated from swamp white grapefruit seeds and plays an anticancer role by inducing apoptosis. |
| M4396 | Fraxetin | Fraxetin is separate from Cortex Fraxini. Fraxetin has anti-tumor, antioxidant and anti-inflammatory effects. Fraxetin can induce apoptosis. |
| M4387 | Carnosic-acid | Carnosic acid inhibits oxidative stress and inflammation, inhibits cell proliferation, and has antibacterial activity. |
| M4380 | Curcumol | Curcumol ((-) -curcumol) is a bioactive sesquiterpene with many pharmacological activities, such as anti-cancer, anti-microbial, anti-fungal, antiviral and anti-inflammatory. Curcumol can effectively induce apoptosis in many cancer cells by targeting key signaling pathways such as MAPK/ERK, PI3K/Akt and NF-κB, which are often abnormally regulated in several cancers. |
| M4362 | Polyphyllin-II | Polyphyllin II is one of the most important saponins in Polyphyllin, which has toxic effects on a variety of cancer cells. Polyphyllin II induces apoptosis through caspases activation and cell cycle arrest. |
| M4358 | Caudatin | Caudatin is a steroid substance in Polygonum multiflorum, which can inhibit cell cycle and induce apoptosis, and has anti-tumor and anti-angiogenesis effects. |
| M4331 | Paederosidic-acid | Paederosidic acid, isolated from P. scandens, has anticancer and anti-inflammatory activities. Paederosidic acid inhibits lung cancer cells by inducing mitochondria - mediated apoptosis. |
| M4315 | Lucidenic-acid-B | Lucidenic acid B is a natural product isolated from Ganoderma lucidum, which can induce tumor cell apoptosis, activation of caspase-9 and caspase-3, and cleavage of PARP. Lucidenic acid B had no effect on cell cycle and no effect on necrotic cells. |
| M4307 | Ganoderenic-acid-D | Ganoderenic acid D is a reishi extract (GLE), triterpenoids. Ganoderenic acid D inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis apoptosis. |
| M4305 | Ganoderic-acid-A | Ganoderic-acid-A inhibits of the JAK-STAT3 signaling pathway, also inhibit proliferation, viability, ROS. |
| M4290 | Atractylenolide-III | Atractylenolide III (ATL III) is the main component of rhizome of Atractylenolide, which can induce apoptosis of lung cancer cells. |
| M4289 | Atractylenolide-II | Atractylenolide II(Atractylenolide II) is a sesquiterpenoid compound isolated from dry rhizome of Atractylodes macrocephala and has anti-proliferative activity. |
| M4262 | Tubeimoside-I | Tubeimoside I, an extract of Fritillaria fritillaria, has been proved to be an effective antitumor agent for various human cancers. |
| M4255 | Gomisin-N | Gomisin N is isolated from Schisandra chinensis and has good effects on promoting sleep and tranquillity in animal models. Gomisin N could be used for allergy studies. Gomisin N is also an anti-tumor agent with the ability to increase anti-tumor growth by inducing apoptosis of cancer cells. |
| M4250 | Schisandrin-C | Schisandrin-C is a natural product extracted from seeds, stems and other plants of Schisandra chinensis (Turcz.) Baill, which has antiviral, anti-cancer, anti-inflammatory and other activities. |
| M4226 | Liensinine Perchlorate | Liensinine Perchlorate, a component of Nelumbo Nucifera Gaertn, has antihypertensive and anticancer activities. Liensinine Perchlorate can induce apoptosis in colorectal cancer (CRC) cells. |
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