| Cat.No. | Name | Information |
|---|---|---|
| M1555 | Amyloid β-Peptide (1-42) human,TFA | Amyloid β-Peptide (1-42) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease. |
| M6952 | Methoxy-X04 | Methoxy-X04 is a fluorescent amyloid β detector; brain penetrant. |
| M3940 | Ginsenoside Rg1 | Ginsenoside Rg1 is part of a class of triterpene saponins and steroid glycosides. Ginsenoside Rg1 ameliorates the impaired cognitive function, displays promising effects by reducing cerebral Aβ levels. It is found exclusively in the plant genus Panax, or ginseng. |
| M28164 | RU-505 | RU-505 is an effective β-amyloid (Aβ)-fibrinogen interaction inhibitor with IC50s of 5.00 and 2.72 μM in fluorescence polarization (FP) and AlphaLISA assays, respectively. RU-505 is highly permeable to the BBB. RU-505 reduces cerebral amyloid angiopathy (CAA). RU-505 can be used for the research of Alzheimer’s disease (AD). |
| M28123 | Semilicoisoflavone B | Semilicoisoflavone B, an isoflavone, mainly derived from Glycyrrhiza uralensis Fisch.. Semilicoisoflavone B reduces amyloid β (Aβ) secretion by inhibiting β-secretase-1 (BACE1) expression and activity. Semilicoisoflavone B decreases BACE1 expression mainly through increasing PPARγ expression and inhibiting STAT3 phosphorylation. |
| M27909 | CRANAD-2 | CRANAD-2 is a near-infrared (NIR) Aβ plaque-specific fluorescent probe. CRANAD 2 penetrates the blood brain barrier and has a high affinity for Aβ aggregates with a Kd of 38 nM. |
| M27647 | MDR-1339 | MDR-1339 (DWK-1339) is an orally active and blood-brain-barrier-permeable Aβ-aggregation inhibitor, used in the research of Alzheimer's disease. |
| M20810 | PBD-150 | PBD-150 is a potent human glutaminyl cyclase (hQC) Y115E-Y117E variant inhibitor with Ki of 60 nM. |
| M20682 | Frentizole | Frentizole is a novel inhibitor of amyloid beta peptide (Abeta) binding alcohol dehydrogenase (ABAD) interaction with IC50 of 200 μM. Frentizole is a nontoxic antiviral and immunosuppressive agent used clinically in rheumatoid arthritis and systemic lupus erythematosus. |
| M20674 | Edonerpic maleate | Edonerpic maleate is a novel neurotrophic agent which can inhibit amyloid-β peptides (Aβ). |
| M20458 | Tabersonine hydrochloride | Tabersonine, an ingredient extracted from the bean of Voacanga africana, is a potent inhibitor against Aβ(1?42) aggregation and toxicity. |
| M19297 | Silybin B | Silybin B (Silibinin B) is the most potent antifibrillogenic and anti-oligomeric component of silymarin and proposes it as a promising anti Alzheimer’s disease agent candidate. |
| M14553 | Hoechst 34580 tetrahydrochloride | Hoechst 34580 tetrahydrochloride is a cell-permeable fluorescent dye for staining DNA and nuclei. |
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