| Cat.No. | Name | Information |
|---|---|---|
| M1555 | Amyloid β-Peptide (1-42) human,TFA | Amyloid β-Peptide (1-42) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease. |
| M6952 | Methoxy-X04 | Methoxy-X04 is a fluorescent amyloid β detector; brain penetrant. |
| M3940 | Ginsenoside Rg1 | Ginsenoside Rg1 is part of a class of triterpene saponins and steroid glycosides. Ginsenoside Rg1 ameliorates the impaired cognitive function, displays promising effects by reducing cerebral Aβ levels. It is found exclusively in the plant genus Panax, or ginseng. |
| M45115 | PMN310 | PMN310 is a beta-amyloid oligomer (AβO) antibody that can be used in studies related to Alzheimer's disease (AD). |
| M42631 | Lanuginosine | Lanuginosine is an AChE inhibitor (IC50: 10.9 μM). |
| M42630 | BIBD-124 | BIBD-124 binds amyloid beta (Aβ) plaque with an IC50 value of 9.51 nM. |
| M42629 | Aβ-IN-6 | Aβ-IN-6 reduces pro-inflammatory cytokine release from microglia cells. |
| M42628 | QR-0217 | QR-0217 is a potent Aβ1-40 aggregation inhibitor with an IC50 value of 7.5 µM. |
| M42627 | β-Sheet Breaker Peptide iAβ5 | β-Sheet Breaker Peptide iAβ5 is a potent degrader of cerebral amyloid-beta (Abeta). |
| M42626 | Aβ/tau aggregation-IN-3 | Aβ/tau aggregation-IN-3 is a potent amyloid protein aggregation inhibitor with an IC50 of 0.85 μM by Aβ-Thioflavin T (Aβ-ThT) functional aggregation assay. |
| M42159 | AChE/Aβ-IN-2 | AChE/Aβ-IN-2 is a potent and orally active inhibitor of acetylcholinesterase (AChE) with IC50 of 135 nM, as well as an antagonist of NMDA receptor with IC50 of 5.054 μM. |
| M42158 | AChE/Aβ-IN-1 | AChE/Aβ-IN-1 is a potent and orally active inhibitor of acetylcholinesterase (AChE) with an IC50 of 86 nM, as well as an antagonist of NMDA receptor with IC50 of 3.876 μM. |
| M41278 | Cannflavin A | Cannflavin A can be isolated from Cannabis sativa L. |
| M31062 | β-Amyloid (22-35) (TFA) | β-Amyloid 22-35 (Amyloid β-Protein 22-35) TFA, the residues 22-35 fragment ofβ-amyloid protein, has a cytotoxic effect on cultured neurons from the rat hippocampus in serum-free medium. |
| M30582 | FSB | FSB is a fluorescent dye that can be used to detect filamentous tau and to label human amyloid lesions with high sensitivity and specificity (excitation: 390 nm, emission: 520 nm). |
| M30470 | K 01-162 | K 01-162 (K162) inhibits the fibril formation of Aβ peptides and eliminates their neurotoxicity. K 01-162 binds with Aβ42 peptide with an EC50 value of 80 nM. K 01-162 binds directly to AβO with a KD value of 19 μM. K 01-162 is capable of penetrating the brain and can be used for the research of Alzheimer’s disease. |
| M30383 | JLK-6 | JLK-6 markedly reduce the production of amyloid β-peptide (Aβ) by amyloid-β Precursor protein (APP) expressing HEK293 cells by affecting the γ-secretase cleavage of APP, with no effect on the cleavage of the Notch receptor. |
| M29922 | PHF6 | PHF6 (VQIVYK) is a self-assembly sequence capable of initiating the full-length tau protein aggregation and is mapped to the third microtubule-binding repeat region of the tau protein. |
| M29108 | (-)Clausenamide | (-)Clausenamide is an active alkaloid isolated from the leaves of Clausena lansium (Lour.) Skeels, and improves cognitive function in both normal physiological and pathological conditions. (-)Clausenamide inhibits β-amyloid (Aβ) toxicity, blocking neurofibrillary tangle formation by inhibiting the phosphorylation of tau protein. (-)Clausenamide exerts a significant neuroprotective activity against Aβ25-35. (-)Clausenamide can be used for researching Alzheimer's disease (AD). |
| M28658 | HEPPS | HEPPS (EPPS) is a buffering agent with the useful pH range from 7.3 ~ 8.7. HEPPS reduces Aβ-aggregate-induced memory deficits and rescues cognitive deficits in mice. EPPS is orally active and penetrates the blood-brain barrier. |
| M28618 | THK-523 | THK-523 has demonstrated its high affinity and selectivity for tau pathology both in vitro and in vivo. 18F-THK523 is a potent tau imaging radiotracer. 18F-THK523 is a potent in vivo tau imaging ligand for Alzheimer's disease. |
| M28532 | β-Amyloid (31-35) | β-Amyloid (31-35) is the shortest sequence of native Amyloid-β peptide that retains neurotoxic activity. |
| M28442 | β-Amyloid (22-35) | β-Amyloid 22-35 (Amyloid β-Protein 22-35), the residues 22-35 fragment ofβ-amyloid protein, has a cytotoxic effect on cultured neurons from the rat hippocampus in serum-free medium. β-Amyloid 22-35 forms aggregates and typical amyloid fibrils resembling those of the β-amyloid protein in neutral buffer solution). |
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