| Cat.No. | Name | Information |
|---|---|---|
| M6952 | Methoxy-X04 | Methoxy-X04 is a fluorescent amyloid β detector; brain penetrant. |
| M3940 | Ginsenoside Rg1 | Ginsenoside Rg1 is part of a class of triterpene saponins and steroid glycosides. Ginsenoside Rg1 ameliorates the impaired cognitive function, displays promising effects by reducing cerebral Aβ levels. It is found exclusively in the plant genus Panax, or ginseng. |
| M1555 | Amyloid β-Peptide (1-42) human,TFA | Amyloid β-Peptide (1-42) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease. |
| M55983 | N-Methylmesoporphyrin IX | N-Methylmesoporphyrin IX (NMM), a widely used G-quadruplex DNA specific fluorescent binder, is an efficient probe for monitoring Aβ fibrillation. |
| M54775 | Methyl tridecanoate | Methyl tridecanoate inhibits β-amyloid aggregation. Methyl tridecanoate weakly inhibits acetylcholinesterase (AChE). |
| M54716 | Trontinemab | Trontinemab is a bispecific human IgG1-κ antibody that targets amyloid β A4 precursor protein (APP) and transferrin receptor (TFRC).Trontinemab may be used in Alzheimer's disease-related studies. |
| M54384 | RAGE antagonist peptide | RAGE antagonist peptide is an advanced glycation end products (RAGE) antagonist. |
| M54071 | Fmoc-Ala-Glu-Asn-Lys-NH2 | Fmoc-Ala-Glu-Asn-Lys-NH2 is a selective asparagine endopeptidase (AEP) inhibitor peptide and suppresses amyloid precursor protein (APP) cleavage. |
| M52464 | β-Amyloid (1-40), FAM-labeled | β-Amyloid (1-40), FAM-labeled is a FAM fluorescently-labelled β-Amyloid (1-40) peptide (λex= 492 nm and λem= 518 nm). |
| M50214 | AC 187 TFA | AC 187 TFA is a potent, orally active and neuroprotective amylin receptor antagonist with an IC50 of 0.48 nM and a Ki of 0.275 nM. AC 187 TFA is more selective for amylin receptors than calcitonin and CGRP receptors. |
| M29729 | Direct Blue 1 | Direct Blue 1 (Chicago Sky Blue 6B) is a counterstain for background autofluorescence in immunofluorescence histochemistry. Direct Blue 1, structurally related to glutamate, is a potent and competitive VGLUT inhibitor without affecting plasma membrane transporters. Direct Blue 1 is the first small molecule PrP ligand capable of inhibiting Aβ binding. |
| M28783 | DC-Chol hydrochloride | DC-Chol hydrochloride could inhibit Aβ40 fibril formation under appropriate experimental conditions. DC-Chol hydrochloride strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner. |
| M25310 | Solanezumab | Solanezumab is a humanized monoclonal IgG1 antibody directed against the mid-domain of the amyloid-β (Aβ) peptide. Solanezumab has the potential for the research of Alzheimer’s disease. |
| M25240 | Bapineuzumab | Bapineuzumab is an anti-β-amyloid protein (APP) monoclonal antibody. Bapineuzumab can be used for the research of Alzheimer’s disease (AD). |
| M24855 | Donanemab | Donanemab (LY3002813) is a humanized IgG1κ monoclonal antibody directed at an N‐terminal pyroglutamate amyloid beta (Aβ) epitope. Donanemab has the potential for early Alzheimer's disease research. |
| M24726 | Birtamimab | Birtamimab (NEOD001) is an investigational monoclonal antibody that specifically and selectively target and clear the amyloid. Birtamimab can be used for the research of light chain amyloidosis. |
| M24639 | Aducanumab | Aducanumab (BIIB037), a human monoclonal antibody selective for aggregated forms of amyloid beta (Aβ). Aducanumab shows brain penetration, and can be used for Alzheimer's disease (AD) research. |
| M24549 | Crenezumab | Crenezumab (MABT 5102A; RG 7412) is a fully humanized anti-Aβ monoclonal antibody that binds multiple forms of Aβ, such as soluble, oligomeric and fibrillar, for use in Alzheimer's disease research. |
| M24541 | Gantenerumab | Gantenerumab is a fully human anti-amyloid-β (Aβ) IgG1 monoclonal antibody demonstrates sustained cerebral amyloid-β binding. Gantenerumab can be used for Alzheimer's disease research. |
| M21812 | ALZ-801 | ALZ-801 is an orally active small molecule compound that is also an inhibitor of β-amyloid A4 (APP) and a precursor compound of homotaurine, which inhibits the formation of neurotoxic amyloid oligomers, and may be used in studies related to Alzheimer's disease (AD). |
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