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AChR/AChE Acetylcholine Receptors/Acetylcholinesterase

Cat.No.  Name Information
M2489 Carbachol chloride Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor.
M3470 Oxybutynin Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
M3190 PNU-282987 PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM.
M5683 Glycopyrrolate Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.
M7227 EVP-6124 hydrochloride EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).
M8888 Donepezil Donepezil(E 2020) is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM, respectively.
M5750 Lobeline HCl Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes.
M3590 Butylscopolamine Bromide Butylscopolamine Bromide, is a peripherally acting antimuscarinic, anticholinergic agent used as an abdominal-specific antispasmodic.
M7940 Mecamylamine hydrochloride Noncompetitive nicotinic acetylcholine receptor antagonist; preferentially blocks nicotinic receptors at autonomic ganglia; crosses blood-brain barrier.
M30915 Pilocarpine  Pilocarpine is a selective M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist.
M2636 Dicyclomine hydrochloride Dicycloamine is an anticholinergic compound, a chemical released by nerves that stimulate muscle by blocking acetylcholine receptors on smooth muscle, a type of muscle.
M2615 Decamethonium Bromide Decamethonium Bromide is a nicotinic AChR partial agonist and neuromuscular blocking agent.
M2613 Darifenacin hydrobromide Darifenacin is a selective M3 muscarinic receptor antagonist with pKi of 8.9.
M2517 Choline Chloride Choline chloride is an essential nutrient that activates alpha7 nicotinic receptors and has analgesic and anti-inflammatory activity.
M2441 Benzethonium Chloride Benzethonium chloride is a potent inhibitor of nAChRs, it inhibits α4β2 nAChRs and α7 nAChRs with IC50 of 49 nM and 122 nM, respectively.
M2397 Anisotropine Methylbromide Anisotropine Methylbromide is a quaternary ammonium compound, inhibits endothelial with IC50 of 162.5 nM and 170.3 nM, respectively.
M2368 Aclidinium Bromide Aclidinium Bromide is a novel long-acting muscarinic antagonist that binds to the human muscarinic receptors AChR M1, M2, M3, M4, and M5 with Ki values of 0.1 nM, 0.14 nM, 0.14 nM, 0.21 nM, and 0.16 nM, respectively. It can be used in chronic obstructive pulmonary disease (COPD) studies.
M2366 Aceclidine hydrochloride Aceclidine is a parasympathomimetic miotic agent used to decreases intraocular pressure.
M2268 Rocuronium bromide Rocuronium bromide (ORG 9426 Bromide) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia.
M2257 Levetiracetam Levetiracetam (UCB L059) is an antiepileptic, it is also a selective M2 muscarinic acetylcholine receptors (mAChR) inhibitor.
M2244 Biperiden hydrochloride Biperiden (KL 373) hydrochloride is a non-selective muscarinic receptor antagonist that competitively binds to M1 muscarinic receptors, thereby inhibiting acetylcholine and enhancing dopamine signaling in the central nervous system.
M2243 Aniracetam Aniracetam is a compound that promotes intellectual development and neuroprotection.
M2170 SVT-40776 SVT-40776 is a novel M3 muscarinic receptor antagonist.
M2037 Fesoterodine fumarate Fesoterodine fumarate (Toviaz) is a novel muscarinic receptor antagonist.
M1866 VU 0255035 VU 0255035 is a highly selective M1 muscarinic acetylcholine receptor (mAChR) antagonist (Ki = 14.87 nM).
M1364 1-Benzyl-1H-indole-2,3-dione 1-Benzyl-1H-indole-2,3-dione
M66216 Choline Chloride-13C3 Choline Chloride-13C3 is the 13C-labeled Choline (chloride). Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate.
M58683 Methoctramine tetrahydrochloride Methoctramine tetrahydrochloride is a potent and cardioselectivity antagonist of M2 muscarinic receptor.
M58357 Dihydro-β-erythroidine hydrobromide Dihydro-β-erythroidine hydrobromide is a potent, orally active, and competitive antagonist of neuronal nAChRs. Dihydro-β-erythroidine hydrobromide shows selectivity for α4β4 and α4β2 nAChRs, with IC50s of 0.19 and 0.37 μM, respectively.
M56811 TAE-1  TAE-1 is a potent inhibitor of AChE and BuChE.




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