| Cat.No. | Name | Information |
|---|---|---|
| M2489 | Carbachol chloride | Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor. |
| M3470 | Oxybutynin | Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. |
| M3190 | PNU-282987 | PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM. |
| M5683 | Glycopyrrolate | Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic. |
| M7227 | EVP-6124 hydrochloride | EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs). |
| M8888 | Donepezil | Donepezil(E 2020) is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM, respectively. |
| M5750 | Lobeline HCl | Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes. |
| M3590 | Butylscopolamine Bromide | Butylscopolamine Bromide, is a peripherally acting antimuscarinic, anticholinergic agent used as an abdominal-specific antispasmodic. |
| M7940 | Mecamylamine hydrochloride | Noncompetitive nicotinic acetylcholine receptor antagonist; preferentially blocks nicotinic receptors at autonomic ganglia; crosses blood-brain barrier. |
| M30915 | Pilocarpine | Pilocarpine is a selective M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist. |
| M3331 | Trospium chloride | Trospium chloride is an orally active, competitive muscarinic cholinergic receptors (mAChRs) antagonist. Trospium chloride binds to muscarinic receptors M1, M2 and M3 with high affinity, but not nicotinic, cholinergic receptors. |
| M3317 | Acetylcholine Chloride | The chemical compound Acetylcholine Chloride is a neurotransmitter in both the peripheral nervous system (PNS) and central nervous system (CNS) in many organisms including humans. |
| M3309 | Bethanechol chloride | Bethanechol chloride is a selective muscarinic receptor agonist without any effect on nicotinic receptors. Bethanechol chloride (0.3-300 μM) significantly reduces ileal pacemaker potentials. |
| M3253 | (-)-Huperzine A | (-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM, exhibiting 200-fold more selectivity for G4 AChE over G1 AChE. Also acts as an NMDA receptor antagonist. Phase 4. |
| M3225 | Atropine sulfate | Atropine sulfate is a competitive muscarinic acetylcholine receptor antagonist. |
| M3046 | Tacrine hydrochloride | Tacrine is a centrally acting anticholinesterase and indirect cholinergic agonist. |
| M3034 | Succinylcholine Chloride Dihydrate | Succinylcholine Chloride Dihydrate is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker. |
| M3025 | Solifenacin succinate | Solifenacin succinate is an anti-muscarinic urinary spasmolysis compound. Solifenacin Succinate (YM905) is a novel muscarinic receptor antagonist with pKis of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively. |
| M2957 | Pridinol Methanesulfonate | Pridenol mesylate is used as an anticholinergic compound and an antiparkinsonian compound. |
| M2947 | Pipenzolate Bromide | Pipenzolate is an antimuscarinic, which binds to muscarinic receptors as an antagonist therefore preventing acetyl choline from binding to the receptors. |
| M2939 | Physostigmine Salicylate | Physostigmine is a parasympathomimetic alkaloid, specifically, a reversible cholinesterase inhibitor. |
| M2909 | Oxybutynin Hydrochloride | Oxybutynin Hydrochloride is an anticholinergic compound used to relieve urinary and bladder load. |
| M2901 | Otilonium Bromide | Otilonium bromide is an antimuscarinic. |
| M2836 | Mepenzolate Bromide | Mepenzolate bromide is an orally administered muscarinic receptor antagonist with Kis of 0.68 and 2.6 nM for hM2R and hM3R, respectively. Mepenzolate bromide is a GPR109A inhibitor. Mepenzolate is a post-ganglionic parasympathetic inhibitor, it decreases gastric acid and pepsin secretion and suppresses spontaneous contractions of the colon. |
| M2762 | Hyoscyamine | Hyoscyamine is an AChR inhibitor with IC50 of 7.5 nM. |
| M2758 | Homatropine Methylbromide | Homatropine Methylbromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively. |
| M2757 | Homatropine Bromide | Homatropine Bromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively. |
| M2754 | Hexamethonium Bromide | Hexamethonium Bromide is a selective antagonist of neuronal-type nicotinic AChR in ganglia. |
| M2753 | Hemicholinium 3 | Hemicholinium 3 is a compound which blocks the reuptake of choline by the high-affinity choline transporter (ChT) at the presynapse. Hemicholinium 3 is a competitive inhibitor of the high affinity choline transporter (HACU) with a Ki value of 25 nM. |
| M2642 | Diphemanil Methylsulfate | Diphemanil Methylsulfate is a quaternary ammonium anticholinergic, it binds muscarinic acetycholine receptors (mAchR). |
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