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AChR/AChE Acetylcholine Receptors/Acetylcholinesterase

Cat.No.  Name Information
M2489 Carbachol chloride Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor.
M3470 Oxybutynin Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
M3190 PNU-282987 PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM.
M5683 Glycopyrrolate Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.
M7227 EVP-6124 hydrochloride EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).
M8888 Donepezil Donepezil(E 2020) is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM, respectively.
M5750 Lobeline HCl Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes.
M3590 Butylscopolamine Bromide Butylscopolamine Bromide, is a peripherally acting antimuscarinic, anticholinergic agent used as an abdominal-specific antispasmodic.
M7940 Mecamylamine hydrochloride Noncompetitive nicotinic acetylcholine receptor antagonist; preferentially blocks nicotinic receptors at autonomic ganglia; crosses blood-brain barrier.
M30915 Pilocarpine  Pilocarpine is a selective M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist.
M8262 HI-6 Asoxime dichloride (HI-6) is an efficient oxime cholinesterase reactivator that is used as an antidote for organophosphates (Ops) exposure.
M8028 Propantheline bromide Propantheline bromide is an orally active mAChR antagonist that inhibits acetylcholine action at postganglionic synapses, and can be used in studies related to smooth muscle dysfunction as well as gastrointestinal spasms.
M7853 Ipratropium bromide monohydrate Nonselective muscarinic acetylcholine receptor antagonist; bronchodilator.
M7585 Atropine Atropine (Tropine tropate) is a competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors. Atropine inhibits ACh-induced relaxations in human pulmonary veins. Atropine can be used for research of anti-myopia and bradycardia.
M7517 Acotiamide hydrochloride Acotiamide Hydrochloride is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. It is a new orally active selective acetylcholinesterase inhibitor.
M7472 VU 0365114 VU 0365114 is a positive allosteric modulator of M5 receptors.
M7141 Pirenzepine dihydrochloride Pirenzepine dihydrochloride is a selective M1 muscarinic antagonist.
M6941 McN-A 343 McN-A 343 is a selective M 1 muscarinic agonist.
M6350 5-Methylfurmethiodide 5-Methylfurmethiodide is a potent muscarinic agonist.
M6341 4-Acetyl-1,1-dimethylpiperazinium iodide 4-Acetyl-1,1-dimethylpiperazinium iodide is a nicotinic agonist.
M6335 3-Bromocytisine 3-Bromocytisine is a potent agonist of α4β4, α4β2 and α7 nACh receptors.
M6273 Varenicline tartrate Varenicline Tartrate is a nicotinic AChR partial agonist, used to treat nicotine addiction.
M6268 Varenicline Varenicline (CP 526555) is a selective α4β2 nicotinic receptor partial agonist, it stimulates nicotine receptors more weakly than nicotine itself does.
M6127 TD-4208 Revefenacin (TD-4208; GSK1160724) is a novel and potent muscarinic receptor antagonist that has a high affinity and long residence time at the M3 receptor, and demonstrates in vitro kinetic selectivity for M3 over M2 muscarinic receptor subtype and no meaningful off-target activity.
M6040 Tropicamide Tropicamide (Ro 1-7683) is an anticholinergic and a muscarinic receptor subtype M4-preferring antagonist with IC50 of 8.0 nM.
M6032 Trihexyphenidyl hydrochloride Trihexyphenidyl hydrochloride is a potent and selective M1 muscarinic receptor antagonist. Trihexyphenidyl hydrochloride shows anticholinergic activity.
M6017 Tiotropium Bromide hydrate Tiotropium Bromide hydrate is an anticholinergic and bronchodilator and a muscarinic receptor antagonist.
M6016 Tiotropium Bromide Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel.
M5970 Solifenacin HCl Solifenacin Hcl(YM905 Hcl; Vesicare Hcl) is a muscarinic receptor antagonist.
M5937 Rivastigmine (tartrate) Rivastigmine Tartrate is a cholinesterase inhibitor with IC50 of 5.5 μM, and used as a parasympathomimetic or cholinergic agent for the treatment of mild to moderate Alzheimer disease.




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