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AChR/AChE Acetylcholine Receptors/Acetylcholinesterase

Cat.No.  Name Information
M2489 Carbachol chloride Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor.
M3470 Oxybutynin Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
M3190 PNU-282987 PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM.
M5683 Glycopyrrolate Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.
M7227 EVP-6124 hydrochloride EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).
M8888 Donepezil Donepezil(E 2020) is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM, respectively.
M5750 Lobeline HCl Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes.
M3590 Butylscopolamine Bromide Butylscopolamine Bromide, is a peripherally acting antimuscarinic, anticholinergic agent used as an abdominal-specific antispasmodic.
M7940 Mecamylamine hydrochloride Noncompetitive nicotinic acetylcholine receptor antagonist; preferentially blocks nicotinic receptors at autonomic ganglia; crosses blood-brain barrier.
M30915 Pilocarpine  Pilocarpine is a selective M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist.
M42651 AChE-IN-31 AChE-IN-31 is a non-competitive AChE inhibitor with potential for the study of Alzheimer's disease.
M42650 hAChE-IN-4 hAChE-IN-4 is a potent, blood-brain barrier-permeable hAChE inhibitor with IC50 of 0.25 μM.
M42649 hAChE/hBACE-1-IN-1 hAChE/hBACE-1-IN-1 is an orally active inhibitor of hAChE with blood-brain permeability.
M42648 Hydrangenol 8-O-glucoside Hydrangenol 8-O-glucoside (Hydrangenol 8-O-β-D-glucopyranoside) can be isolated from Hydrangea macrophyllu.
M42647 Zanapezil fumarate Zanapezil (TAK-147) fumarate is a potent, reversible and selective acetylcholine esterase (AChE) inhibitor.
M42646 SD-6 SD-6 is an orally active inhibitor of hAChE and hBChE with IC50 values of 0.907 µM and 1.579 µM, respectively.
M42644 hBChE-IN-2 hBChE-IN-2 is a butyrylcholinesterase (BChE) inhibitor (IC50 of 0.62 μM) and a cannabinoid receptor 2 (CB2R) agonist.
M42643 Octahydroaminoacridine Octahydroaminoacridine, a Tacrine analogue, is an acetylcholinesterse (AChE) and butyrylcholinesterase (BChE) inhibitor.
M42642 BChE-IN-17 BChE-IN-17 is a potent and selective BChE inhibitor with IC50s of 10.5 nM and 32.5 nM for eqBChE and hBChE, respectively.
M42641 AChE-IN-34 AChE-IN-34 is a potent and selective AChE inhibitor with an IC50 value of 3.98 µM with no significant inhibition against BChE.
M42640 BChE-IN-19 BChE-IN-19 is a para-substituted derivative of indone (7b) with inhibitory activity of butyryl cholinesterase (BChE) (IC50=0.04 μM).
M42639 Methyl ganoderate A acetonide Methyl ganoderate A acetonide, a lanostane triterpene, is a natural product that could be isolated from the fruiting bodies of Ganoderma lucidum.
M42638 hAChE/hBACE-1-IN-2 hAChE/hBACE-1-IN-2 is a potent, orally active, blood-brain barrier transboundary triple inhibitor of hAChE, hBChE, and HACE-1 with IC50s of 0.113 μM, 1.48 μM and 0.38 μM, respectively.
M42637 SB-1436 SB-1436 is an Cholinesterase (ChE) inhibitor, inhibits AChE, BChE and rHuAChE with IC50s of 0.176, 0.37 and 0.08 μM, respectively.
M42214 Tebanicline hydrochloride Tebanicline hydrochloride (Ebanicline hydrochloride) is a nAChR modulator with potent, orally effective analgesic activity.
M42213 CVN417 CVN417 is an orally active α6 subunit-containing nAChR antagonist, modulating phasic dopaminergic neurotransmission in an impulse-dependent manner.
M42212 Epiboxidine hydrochloride Epiboxidine hydrochloride is a potent and selective neural nAChR agonist with Kis of 0.46 nM and 1.2 nM for rat and human α4β2 nAChRs, respectively.
M42211 TC-1698 TC-1698 is a selective α7 nicotinic acetylcholine receptors agonist with EC50 value of 0.16 μM and 0.46 μM for monkey α7 nicotinic receptor and human α7 nicotinic receptor, respectively.
M41867 Oxyphenonium bromide Oxyphenonium bromide is an antiacetylcholine compound.
M41866 Nitrocaramiphen hydrochloride Nitrocaramiphen hydrochloride is a selective M1 receptor antagonist (Ki: 5.5 nM).




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