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AChR/AChE Acetylcholine Receptors/Acetylcholinesterase

Cat.No.  Name Information
M2489 Carbachol chloride Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor.
M3470 Oxybutynin Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
M3190 PNU-282987 PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM.
M5683 Glycopyrrolate Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.
M7227 EVP-6124 hydrochloride EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).
M8888 Donepezil Donepezil(E 2020) is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM, respectively.
M5750 Lobeline HCl Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes.
M3590 Butylscopolamine Bromide Butylscopolamine Bromide, is a peripherally acting antimuscarinic, anticholinergic agent used as an abdominal-specific antispasmodic.
M7940 Mecamylamine hydrochloride Noncompetitive nicotinic acetylcholine receptor antagonist; preferentially blocks nicotinic receptors at autonomic ganglia; crosses blood-brain barrier.
M30915 Pilocarpine  Pilocarpine is a selective M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist.
M44846 Echimidine N-oxide Echimidine N-oxide, a pyrrolizidine alkaloid, has acetylcholinesterase (AChE) inhibitory activity (IC50=0.347 mM).
M44781 Apohyoscine Aposcopolamine is an alkaloid that can be isolated from Datura ferox. Aposcopolamin can closely binds with ACHE, ADRA2A and CHRM2. Aposcopolamine can be used for the research of Alzheimer's disease.
M42669 hBChE-IN-1 hBChE-IN-1 and highly selective over hAChE.
M42668 GSK1034702 GSK1034702 is a M1 mAChR allosteric agonist.
M42667 AChE-IN-40 AChE-IN-40 is an AChE inhibitor (IC50: 120 nM).
M42666 AChE-IN-39 AChE-IN-39 is an AChE inhibitor (IC50: 0.058 μM).
M42665 AChE-IN-35 AChE-IN-35 is an AChE inhibitor with the IC50 of 5.88 μM.
M42664 MR2938 MR2938 is a potent AChE inhibitor, with an IC50 of 5.04 μM.
M42663 AChE-IN-30 AChE-IN-30 is an AChE inhibitor with an IC50 value of 4.4 μM.
M42662 hAChE-IN-1 hAChE-IN-1 is a potent hAChE inhibitor with an IC50 of 1.09 μM.
M42661 hAChE-IN-2 hAChE-IN-2 is a potent hAChE inhibitor, with an IC50 of 0.71 μM.
M42660 PD07 PD07 is an orally active AChE inhibitor (IC50: 0.29 μM for hAChE).
M42659 AChE-IN-37 AChE-IN-37 is anacetylcholinesterase inhibitorswith an IC50 of 0.23 μM.
M42658 AChE-IN-36 AChE-IN-36 is anacetylcholinesterase inhibitorswith an IC50 of 0.04 μM.
M42657 AChE-IN-29 AChE-IN-29, 3-OH pyrrolidine derivative, is an cholinesterase (ChE) inhibitor.
M42656 BChE-IN-16 BChE-IN-16 is a highly potent BChE inhibitor with an IC50 of 3.8 nM for hBChE.
M42655 Depramine Depramine (GP 31406) is a tricyclic antidepressant with pharmacologically activity.
M42654 AChE/BChE-IN-12 AChE/BChE-IN-12 inhibitor, with IC50 values of 2.57, 3.26, and 10.65 μM, respectively.
M42653 AChE/BChE-IN-15 AChE/BChE-IN-15 is an AChE/BChE inhibitor, with IC50s of 20 nM and 220 nM respectively.
M42652 TRV-7019 TRV-7019 is a BBB-penetrable radioligand for brain imaging that target butyrylcholinesterase.




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