| Cat.No. | Name | Information |
|---|---|---|
| M2489 | Carbachol chloride | Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor. |
| M3470 | Oxybutynin | Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. |
| M3190 | PNU-282987 | PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM. |
| M5683 | Glycopyrrolate | Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic. |
| M7227 | EVP-6124 hydrochloride | EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs). |
| M8888 | Donepezil | Donepezil(E 2020) is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM, respectively. |
| M5750 | Lobeline HCl | Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes. |
| M3590 | Butylscopolamine Bromide | Butylscopolamine Bromide, is a peripherally acting antimuscarinic, anticholinergic agent used as an abdominal-specific antispasmodic. |
| M7940 | Mecamylamine hydrochloride | Noncompetitive nicotinic acetylcholine receptor antagonist; preferentially blocks nicotinic receptors at autonomic ganglia; crosses blood-brain barrier. |
| M30915 | Pilocarpine | Pilocarpine is a selective M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist. |
| M52759 | α-Conotoxin EI | α-Conotoxin EI is a selective nicotinic acetylcholine α1β1γδ receptor (nAChR) antagonist (IC50=187 nM) and an α3β4 receptor inhibitor. |
| M52758 | α-Conotoxin GI | α-Conotoxin GI has high affinity for nAChR.α-Conotoxin GI is a short peptide toxin that can be isolated from the venom of Conus geographus.α-Conotoxin GI has the similar activity with neuromuscular blocking agent. |
| M52757 | Azemiopsin | Azemiopsin is a potent nicotinic acetylcholine receptor (nAChR) inhibitor with IC50s of 0.18 μM and 22 μM against T. |
| M52756 | Waglerin-1 | Waglerin-1, a 22-amino acid peptide, is a competitive antagonist of the muscle nicotinic receptor (nAChR). |
| M52755 | ACV1 | ACV1 (Vc1.1), an α-Conotoxin, is a selective α9α10 nAChR antagonist with an IC50 of 19 nM. |
| M52412 | Glycyl-L-glutamic acid | Glycyl-L-glutamic acid is a neurotrophic factor (NF) in vivo, and exerts function of maintenance of AChE content and activity. |
| M52411 | Fasciculin-II | Fasciculin-II (Fas-2) is a potential inhibitor of acetylcholinesterase (AChE). |
| M52410 | SP-10 | SP-10 is a small peptide derived from S protein with an IC50 value of 1.88 nM for blocks the interaction between S protein and ACE2. |
| M49735 | hAChE-IN-6 | hAChE-IN-6 is a brain penetrant AChE inhibitor with an IC50 of 0.16 μM. |
| M49734 | AChE/GSK-3β-IN-1 | AChE/GSK-3β-IN-1 is a potent, dual AChE/GSK-3β inhibitor with IC50 values of 1.2, 149.8 and 22.4 nM for hAChE , hBChE and hGSK-3β, respectively. |
| M49732 | α7 nAchR-JAK2-STAT3 agonist 1 | α7 nAchR-JAK2-STAT3 agonist 1 is a potent α7 nAchR-JAK2-STAT3 agonist, with an IC50 value of 0.32 μM for nitric oxide (NO). |
| M45391 | NBI-1117570 | NBI-1117570 is an oral muscarinic M1/M4 selective dual agonist for studies related to neurological disorders. |
| M45390 | NBI-1117568 | NBI-1117568 is an oral selective muscarinic M4 receptor agonist for use in Alzheimer's disease as well as in studies related to schizophrenia. |
| M45117 | Xanomeline tartrate | Xanomeline tartrate is a potent and selective muscarinic type 1 and type 4 (M1/M4) receptor agonist that increases neuronal excitability and can be used in studies of neurological disorders such as schizophrenia. |
| M44961 | O-Desmethyl galanthamine | O-Desmethyl Galanthamine (Sanguinine) is galanthamine-type alkaloid. O-Desmethyl Galanthamine is an acetylcholinesterase (AChE) inhibitor, with an IC50 1.83 μM. |
| M44950 | N-Methylcalycinine | N-Methylcalycinine is a nature product with AChE inhibitory activity. |
| M44935 | Microgrewiapine A | Microgrewiapine A is an antagonist of nAChR. |
| M44879 | Homatropine hydrochloride | Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects. |
| M44877 | Homatropine | Homatropine is an orally active muscarinic acetylcholine receptor antagonist and can be used as an anticholinergic agent. |
| M44873 | Heliosupine N-oxide | Heliosupine N-oxide, Heliosupin metabolite, inhibits muscarinic acetylcholine receptor (mAChR) with the IC50 of 350 μM. Heliosupine N-oxide is a pyrrolizidine alkaloid (PA). |
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