| Cat.No. | Name | Information |
|---|---|---|
| M2489 | Carbachol chloride | Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor. |
| M3470 | Oxybutynin | Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. |
| M3190 | PNU-282987 | PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM. |
| M5683 | Glycopyrrolate | Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic. |
| M7227 | EVP-6124 hydrochloride | EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs). |
| M8888 | Donepezil | Donepezil(E 2020) is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM, respectively. |
| M5750 | Lobeline HCl | Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes. |
| M3590 | Butylscopolamine Bromide | Butylscopolamine Bromide, is a peripherally acting antimuscarinic, anticholinergic agent used as an abdominal-specific antispasmodic. |
| M7940 | Mecamylamine hydrochloride | Noncompetitive nicotinic acetylcholine receptor antagonist; preferentially blocks nicotinic receptors at autonomic ganglia; crosses blood-brain barrier. |
| M30915 | Pilocarpine | Pilocarpine is a selective M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist. |
| M54385 | α-Conotoxin MII | α-Conotoxin MII (α-CTxMII), a 16-amino acid peptide from the venom of the marine snail Conus magus, potently blocks nicotinic acetylcholine receptors (nAChRs) composed of α3β2 subunits, with an IC50 of 0.5 nM. |
| M54173 | COG 133 TFA | COG 133 TFA is a fragment of Apolipoprotein E (APOE) peptide. |
| M53102 | G-Protein antagonist peptide | G-Protein antagonist peptide is the substance P-related peptide that inhibits binding of G proteins to their receptors. |
| M53101 | α-Conotoxin M I | α-Conotoxin M I is a potent and selective inhibitor of mAChR and α1β1γδ nAChR, but has no effect on nicotine-stimulated dopamine release. |
| M52775 | α-Conotoxin PnIA | α-Conotoxin PnIA, a potent and selective antagonist of the mammalian α7 nAChR, has the potential for the research of neurological conditions such as neuropathic pain and Alzheimer’s disease. |
| M52774 | κ-Bungarotoxin | κ-Bungarotoxin (κ-Bgt) is a potent, selective, and slowly reversible antagonist of α3β2 neuronal nicotinic acetylcholine receptors with an IC50 of 2.30 nM. |
| M52773 | Rabies Virus Matrix Protein Fragment(RV-MAT) | Rabies Virus Matrix Protein Fragment (RV-MAT) is a polypeptide. |
| M52772 | αO-Conotoxin GeXIVA | αO-Conotoxin GeXIVA is a potent α9α10 nAChR antagonist with an IC50 of 12 nM against rat α9α10. |
| M52771 | αA-Conotoxin OIVA | αA-Conotoxin OIVA (αA-OIVA) is a selective nAChR antagonist with an IC50 of 56 nM against mammalian fetal muscle nAChR. |
| M52770 | αA-Conotoxin PIVA | αA-Conotoxin PIVA is a selective mouse musclenAChR inhibitor with IC50 for adult and fetal mouse musclenAChR sub> values are 2.3 nM and 22 nM respectively. |
| M52769 | α-Conotoxin AuIA | α-Conotoxin AuIA is a potent and selective α3β4 n-nAChR inhibitor. |
| M52768 | α-Conotoxin BuIA | α-Conotoxin BuIA is a paralytic peptide neurotoxin and a competitive nAChR antagonist, with IC50s of 0.258 nM (α6/α3β2), 1.54 nM (α6/α3β4), 5.72 nM (α3β2), respectively. |
| M52767 | α-Conotoxin Im-I | α-Conotoxin Im-I is a selective α7/α9 nAChR antagonist, blocking α7 nicotinic receptors with the highest apparent affinity, while having an 8-fold lower affinity for homomeric α9 nicotinic receptors. |
| M52766 | α-Conotoxin MrIC | α-Conotoxin MrIC is an α7nAChR biased agonist. |
| M52765 | α-Conotoxin PeIA | α-Conotoxin PeIA is an analgesic α-conotoxin.α-Conotoxin PeIA inhibits the α6β4, α9α10 and α3β2 nAChR.α-Conotoxin PeIA is also a potent inhibitor of N-type calcium channel via GABAB receptor activation. |
| M52764 | α-Conotoxin RgIA | α-Conotoxin RgIA (α-RgIA) is a specific α9α10 nAChR antagonist. |
| M52763 | α-Conotoxin S IA | α-Conotoxin SIA is a selective nicotinic acetylcholine receptor (nAChR) antagonist with high affinity for the muscle nAChR. |
| M52762 | α-Conotoxin TxID | α-Conotoxin TxID is a potent α3β4 nAChR antagonist with an IC50 value of 12.5 nM. |
| M52761 | α-Conotoxin GIC | α-Conotoxin GIC is a potent and selective α3β2 nicotinic antagonist with an IC50 of 1.1 nM. |
| M52760 | α-Conotoxin GID | α-Conotoxin GID is a paralytic peptide neurotoxin and a selective antagonist of nAChR, with IC50s of 5 nM (α7), 3 nM (α3β2), 150 nM (α4β2), respectively. |
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