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AChR/AChE Acetylcholine Receptors/Acetylcholinesterase

Cat.No.  Name Information
M2489 Carbachol chloride Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor.
M3470 Oxybutynin Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
M3190 PNU-282987 PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM.
M5683 Glycopyrrolate Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.
M7227 EVP-6124 hydrochloride EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).
M8888 Donepezil Donepezil(E 2020) is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM, respectively.
M5750 Lobeline HCl Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes.
M3590 Butylscopolamine Bromide Butylscopolamine Bromide, is a peripherally acting antimuscarinic, anticholinergic agent used as an abdominal-specific antispasmodic.
M7940 Mecamylamine hydrochloride Noncompetitive nicotinic acetylcholine receptor antagonist; preferentially blocks nicotinic receptors at autonomic ganglia; crosses blood-brain barrier.
M30915 Pilocarpine  Pilocarpine is a selective M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist.
M56527 PHA-543613 hydrochloride  PHA-543613 hydrochloride is an oral or active α7 nAChR agonist with brain permeability, For α3β4, α1β1γδ, α4β2 and 5-HT3 receptors selective.
M56526 RJR-2429 dihydrochloride  RJR 2429 hydrochloride is a α4β2 and α7 nAChR agonist.
M56525 PHA-543613 dihydrochloride  PHA-543613 dihydrochloride is a potent, orally active, brain-penetrant and selective α7 nAChR agonist with a Ki value of 8.8 nM.
M56524 Tebanicline dihydrochloride Tebanicline dihydrochloride (Ebanicline dihydrochloride) is a nAChR modulator with potent, orally effective analgesic activity.
M56523 (±)-Anatoxin A fumarate  (±)-Anatoxin A fumarate is a potent nicotinic receptor agonist and exhibits Ki values of 1.25 nM and 1.84 μM for binding to putative α4β2-type nAChR and α7-type nAChR in rat brain membranes, respectively.
M56522 5-Iodo-A-85380 dihydrochloride 5-Iodo-A-85380 dihydrochloride is a selective ligand of nAChR.
M56255 AC-42  AC-42 is a poent M1 muscarinic selective allosteric agonist with EC50s of 805 nM and 220 nM for human wild-type and Y381A mutated M1 receptors, respectively.
M56254 ASP8302  ASP8302 is a positive allosteric modulator of muscarinic M3 Receptor.
M56253 VU6019650  VU6019650 is a potent and selective orthosteric antagonist of M5 mAChR (IC50=36 nM), can be used for opioid use disorder (OUD) relief.
M56252 LY 2033298  LY 2033298 is a selective positive allosteric modulator of the muscarinic M4 receptor.
M56251 mAChR-IN-1  mAChR-IN-1 is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 nM.
M56250 Zamifenacin Zamifenacin (UK-76654) is a potent gut-selective muscarinic M3 receptor antagonist.
M56249 Tolterodine Tolterodine(PNU-200583) is a potent muscarinic receptor antagonists that show selectivity for the urinary bladder over salivary glands in vivo.
M56248 N-Demethyl MK-6884  N-Demethyl MK-6884 is a potent M4 mAChR allosteric modulator.
M56247 AC-42 hydrochloride  AC-42 hydrochloride is the hydrochloride salt form of AC-42.
M56246 Rapacuronium bromide Rapacuronium bromide (Org 9487), a non-depolarizing neuromuscular blocker, is an allosteric modulator of muscarinic acetylcholine receptor (mAChR).
M56245 Zamifenacin fumarate Zamifenacin fumarate (UK-76654 fumarate) is a potent gut-selective muscarinic M3 receptor antagonist.
M56244 mAChR-IN-1 hydrochloride  mAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 nM.
M54823 THRX-160209 THRX-160209 is a potent antagonist at the M(2) muscarinic acetylcholine (ACh) receptor subtype that was designed using a multivalent strategy, simultaneously targeting the orthosteric site and a nearby site known to bind allosteric ligands.
M54437 Catestatin Catestatin is a 21-amino acid residue, cationic and hydrophobic peptide.




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