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AChR/AChE Acetylcholine Receptors/Acetylcholinesterase

Cat.No.  Name Information
M2489 Carbachol chloride Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor.
M3470 Oxybutynin Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
M3190 PNU-282987 PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM.
M5683 Glycopyrrolate Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.
M7227 EVP-6124 hydrochloride EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).
M8888 Donepezil Donepezil(E 2020) is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM, respectively.
M5750 Lobeline HCl Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes.
M3590 Butylscopolamine Bromide Butylscopolamine Bromide, is a peripherally acting antimuscarinic, anticholinergic agent used as an abdominal-specific antispasmodic.
M7940 Mecamylamine hydrochloride Noncompetitive nicotinic acetylcholine receptor antagonist; preferentially blocks nicotinic receptors at autonomic ganglia; crosses blood-brain barrier.
M30915 Pilocarpine  Pilocarpine is a selective M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist.
M56810 PE154  PE154 is a potent fluorescent inhibitor of human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC50s=280 pM and 16 nM, respectively).
M56809 AChE-IN-23  AChE-IN-23 is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 48.3 μM.
M56808 Carlina oxide  Carlina oxide is an AChE inhibitor and antioxidant that kills Culex pipiens larvae (LC50=1.39 μg/mL).
M56807 Ambenonium chloride Ambenonium (WIN 8077) chloride is an orally active and reversible inhibitor of Acetyicholinesterase (AChE) with high affinity.
M56806 Pseudocoptisine acetate Pseudocoptisine (Isocoptisine) acetate is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber.
M56805 Pseudocoptisine chloride Pseudocoptisine (Isocoptisine) chloride is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber.
M56541 bPiDDB  bPiDDB is a potent nAChR antagonist.
M56540 BNC375  BNC375 is a potent, selective, and orally available type I positive allosteric modulator of α7 nAChRs with an EC50 of 1.9 μM.
M56539 ABT-107  ABT-107 is a selective α7 neuronal nicotinic receptor agonist.
M56538 AZD0328  AZD0328 is a selective α7 nAChR partial agonist.
M56537 SUVN-911  SUVN-911 is a potent, selective, brain penetrated and orally bioavailable neuronal nicotinic acetylcholine α4β2 receptor antagonist, with a Ki of 1.5 nM.
M56536 PHA 568487  PHA 568487 a selective agonist of alpha-7 nicotinic acetylcholine receptor (α-7 nAchR).PHA 568487 reduces neuroinflammation and oxidative stress.
M56535 Ropanicant Ropanicant (SUVN-911 free base) is a novel, potent, selective, and orally active neuronal nicotinic acetylcholine α4β2 receptor antagonist for the research of depression.
M56534 Flupyrimin  Flupyrimin acts as an antagonist at the insect nicotinic acetylcholine receptor (nAChR).
M56533 Tebanicline Tebanicline, an analogue of epibatidine, is a neuronal nicotinic acetylcholine receptor agonist.
M56532 R-(+)-Cotinine R-(+)-Cotinine ((+)-Cotinine), a Nicotine metabolite, lacks significant activity across a wide range of pharmacological targets.
M56531 nAChR agonist 1  nAChR agonist 1 is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR).
M56530 PHA 568487 free base  PHA 568487 free base is a selective alpha 7 nicotinic acetylcholine receptor (α-7 nAchR) agonist.
M56529 (±)-Epibatidine (±)-Epibatidine is a nicotinic agonist.
M56528 SSR180711 hydrochloride  SSR180711 hydrochloride is an orally active, selective and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist.




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