| Cat.No. | Name | Information |
|---|---|---|
| M10446 | 1400W dihydrochloride | 1400W dihydrochloride is a potent and selective inhibitor of human inducible NO synthase with Ki values of 7 nM. 1400W inhibits iNOS induction in microglial cells, and reduces generation of NO, thereby mitigating oxidative stress and neuronal cell apoptosis in the rat cerebral cortex. |
| M20781 | Bendazol | Bendazol (2-Benzylbenzimidazole, Dibazol, Dibazole, Bendazole, Tromasedan) is a hypotensive drug that enhances NO synthase activity in renal glomeruli and collecting tubules. Bendazol inhibits the progression of form-deprivation myopia (FDM) and suppresses the upregulation of HIF-1α. |
| M19197 | Physalin L | Physalin L inhibits LPS-induced NO production in macrophages with the average inhibitory rate of 70.97%. Anti-inflammatory activity. |
| M19167 | Amaroswerin | Amaroswerin is a bioactive secoiridoid glucoside from Swertia mussotii. Amaroswerin inhibits NO release with an IC50 value of 5.42 μg/mL in RAW264.7 cells. |
| M14101 | Syzalterin | Syzalterin is an inhibitor of NO production with an IC50 of 1.87 μg/mL. |
| M14099 | L-NIL | L-NIL is an inducible NO synthase inhibitor, with an IC50 of 3.3 μM for miNOS. |
| M14098 | GW274150 phosphate | GW274150 phosphate is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC50=2.19 μM; Kd=40 nM) and rat iNOS (ED50=1.15 μM). |
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