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NO Synthase Nitric oxide synthase (NOS)

Cat.No.  Name Information
M10446 1400W dihydrochloride 1400W dihydrochloride is a potent and selective inhibitor of human inducible NO synthase with Ki values of 7 nM. 1400W inhibits iNOS induction in microglial cells, and reduces generation of NO, thereby mitigating oxidative stress and neuronal cell apoptosis in the rat cerebral cortex.
M20781 Bendazol Bendazol (2-Benzylbenzimidazole, Dibazol, Dibazole, Bendazole, Tromasedan) is a hypotensive drug that enhances NO synthase activity in renal glomeruli and collecting tubules. Bendazol inhibits the progression of form-deprivation myopia (FDM) and suppresses the upregulation of HIF-1α.
M19197 Physalin L Physalin L inhibits LPS-induced NO production in macrophages with the average inhibitory rate of 70.97%. Anti-inflammatory activity.
M19167 Amaroswerin Amaroswerin is a bioactive secoiridoid glucoside from Swertia mussotii. Amaroswerin inhibits NO release with an IC50 value of 5.42 μg/mL in RAW264.7 cells.
M14101 Syzalterin Syzalterin is an inhibitor of NO production with an IC50 of 1.87 μg/mL.
M14099 L-NIL L-NIL is an inducible NO synthase inhibitor, with an IC50 of 3.3 μM for miNOS.
M14098 GW274150 phosphate GW274150 phosphate is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC50=2.19 μM; Kd=40 nM) and rat iNOS (ED50=1.15 μM).




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