| Cat.No. | Name | Information |
|---|---|---|
| M4464 | 9-methoxycamptothecine | 10-methoxycamptothecin, a natural bioactive derivative of camptothecin (CPT) isolated from Camptotheca acuminata, has been proven to have high anticancer properties. It was found that 10-methoxycamptothecin had higher cytotoxicity than 10-hydroxycamptothecin by measuring its antitumor activity against cell line 2774. |
| M4462 | Oroxin-B | Oroxin B (OB) is a flavonoid isolated from the traditional Chinese herb Oroxylum indicum (L.) Vent. Oroxin B (OB) can inhibit hepatoma cells by up-regulating PTEN, down-regulating COX-2, VEGF, PI3K and P-Akt, and induce early apoptosis. Oroxin B (OB) induces suppressive ER stress in malignant lymphoma cells. |
| M4461 | Oroxin-A | Oroxin-A acts as a partial PPARγ agonist that can activate PPARγ transcriptional activation. Oroxin A activates PPARγ by docking into the PPARγ protein ligand-binding domain. Oroxin A also exhibits an inhibitory activity against α-glucosidase and an antioxidant capacity. |
| M4460 | Oroxylin-A | Oroxylin A is an active flavonoid that inhibits the phosphorylation of MDM2 and SIRT1 through the inhibition of CDK9, thus inhibiting MDM2-mediated degradation of P53 and SIRT1-mediated deacetylation of P53, and ultimately stabilizing the P53 protein.Oroxylin A has strong anticancer activity. |
| M4459 | Oroxyloside | Oroxyloside (Oroxylin A-7-O-glucuronide) is a flavonoid glucuronide isolated from the dried root of Scutellaria baicalensis, with prolyl oligopeptidase (POP) inhibitory activity. |
| M4458 | Tetrahydroberberine | Tetrahydroberberine is an isoquinoline alkaloid isolated from corydalis tuber; has micromolar affinity for dopamine D(2) (pK(i) = 6.08) and 5-HT(1A) (pK(i) = 5.38) receptors but moderate to no affinity for other relevant serotonin receptors (5-HT(1B), 5-HT(1D), 5-HT(3), and 5-HT(4); pK(i) < 5.00). |
| M4456 | Sec-O-Glucosylhamaudol | Sec-o-glucosylhamaudol is a natural product isolated from The apostrophophore, which can reduce the protein level of μ-opioid receptor and can be used for pain relief research. |
| M4455 | 5-O-Methylvisammioside | 5-O-methylvisammioside isa natural compound isolated from parsnip. |
| M4454 | 2-acetylacteoside | 2' -acetylacteoside (2' -acetylacteoside) is a kind of phenylethanol glycoside isolated from Phyllostachys chinensis, which can inhibit erythrocyte hemolysis induced by free radicals and has scavenging activity. |
| M4453 | Tubuloside-A | Tubuloside A is A phenyl ethanol glycoside with antioxidant activity and liver protection activity. |
| M4452 | Echinacoside | Echinacoside is a phenylethanol compound isolated from Cistanche salsa that effectively inhibits the Wnt/β-catenin signaling pathway. Echinacoside plays a neuroprotective role by activating Trk receptors and their downstream signaling pathways. Echinacoside also has significant anti-osteoporosis activity. |
| M4451 | Isoacteoside | Isoacteoside is a natural product that significantly inhibits the formation of glycation end products. |
| M4450 | Acteoside | Acteoside is isolated from Acanthus mollis, acts as an ATP-competitive inhibitor of PKC, with an IC50 of 25 µM, and has antitumor, anti-inflammatory and antineuropathic pain activity. |
| M4449 | Cimigenol-3-O-α-L-arabinoside | Cimiracemoside C, the active ingredient in cohosh, activates AMPK and has anti-diabetes potential. |
| M4448 | Acetylcimigenol-3-O-α-L-arabinopyranside | Acetylshengmanol -3-O-α -L-arabinose is an extract of cohosh. |
| M4447 | 3-Hydroxy-4-methoxycinnamic-acid | Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) is a kind of cinnamic acid derivative with anti - diabetes activity. Isoferulic acid (3-hydroxy-4-methoxycinnamic acid) binds and activates α 1-adrenergic receptor (IC50=1.4 μM), Enhanced β -endorphin secretion (EC50=52.2 nM) and increased in vitro glucose use. Isoferulic acid also has activity against influenza virus. |
| M4446 | Cimifugin | Cimifugin (Cimitin) is the bioactive ingredient of Chinese herbal medicine Saposhnikovia divaricate. Cimifugin inhibits allergic inflammation by regulating tight junctions to reduce epithelial-derived active key factors. |
| M4445 | Prim-o-glucosylcimifugin | Prim-o-glucosylcimifugin has a potent anti-inflammatory effect. INOS and COX-2 expression could be inhibited by regulating JAK2/STAT3 signal transduction. |
| M4444 | 2,3,5,4-tetrahydroxyl-diphenylethylene-2-o-glucoside | 2,3,4', 5-Tetrahydroxystilbene 2-O-D-glucoside was isolated from the roots of polygonum species and inhibited the formation of 5-Hete, HHT and Thromboxane B2. |
| M4443 | Spinosin | Spinosyn is a neuroprotective C-glycoside flavonoid isolated from the seeds of Zizyphus jujube. Spinosyn inhibits the production and polymerization of Aβ1-42 by activating the Nrf2/HO-1 pathway. |
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