| Cat.No. | Name | Information |
|---|---|---|
| M4570 | Palmatine | Palmatine is an orally active and irreversible IDO-1 inhibitor. Palmatine ameliorates colitis induced by Dextran Sulphate Sodium Salt (DSS) by reducing colon injury, preventing intestinal microbiome imbalance and regulating tryptophan catabolism. Palmatine has potential for colitis research. |
| M4569 | AescinIIB | Escin IIb, isolated from horse chestnut seed horse chestnut, has a positive effect on acute inflammation in animals. Escin IIb has a significant protective effect on gastric mucosa injury induced by ethanol. |
| M4568 | Aescin-IIA | Escin IIa, isolated from horse chestnut seed horse chestnut, has a positive effect on acute inflammation in animals. Escin IIa has obvious protective effect on gastric mucosa injury induced by ethanol. |
| M4567 | Escin-IB | Escin IB is a saponin isolated from the skin and endosperm of horse chestnut (Aesculus hippocastanum) seeds. Escin IB has an inhibitory effect on pancreatic lipase activity. |
| M4566 | Escin-IA | Escin IA, a triterpenoid saponin isolated from horse chestnut, inhibits HIV-1 protease with IC50 value of 35 μM. Escin IA has anti-metastasis activity of triple negative breast cancer, and its mechanism includes down-regulation of LOXL expression and inhibition of epithelial mesenchymal transformation. |
| M4565 | (-)-Sparteine-sulfate-pentahydrate | (-)-Sparteine-sulfate-pentahydrate |
| M4564 | Lobetyolin | Lobetyolin is a bioactive compound isolated from Codonopsis Pilosula. Lobetyolin has anti-inflammatory, antioxidant and xanthine oxidase inhibitory activities. Lobetyolin also induces apoptosis by inhibiting ASCT2-mediated glutamine metabolism. |
| M4562 | Cantharidin | Cantharidin is a natural toxin inhibitor of protein phosphatases 1 and 2A (Ki values are 1.1 and 0.19 μM respectively). Displays > 500-fold selectivity over PP2B. |
| M4561 | Sodium-Demethylcantharidate | Sodium Demethylcantharidate is an endogenous metabolite. Sodium Demethylcantharidate induces apoptosis in hepatocellular carcinoma cells via ER stress, it shows excellent anticancer activity against multiple types of cancer. |
| M4560 | Paeonolide | Paeonolide is a plant glycoside containing a non-reducing terminal α -1-arabopyranoside, which is present in the roots of a wide range of plants of the Genus Paeonia. |
| M4559 | Ziyuglycoside-II | Ziyuglycoside II from Sanguisorba officinalis L. Triterpenoid saponins extracted from the. Ziyuglycoside II induces reactive oxygen species (ROS) production and apoptosis. It has anti-inflammatory and anticancer effects. |
| M4558 | Ziyuglycoside-I | Ziyuglycoside I, isolated from S. officinalis root, has anti-wrinkle activity and increases type I collagen expression. Ziyuglycoside I can be used as an active ingredient in cosmetics. Ziyuglycoside I can induce p53-mediated cell cycle arrest and apoptosis, which can be used in the study of triple negative breast cancer. |
| M4557 | Dictamine | Dictamnine (Dictamine) is cytotoxic to human cervical and colon cancer cells, and also has antibacterial and antifungal activities. |
| M4556 | Fraxinellone | Fraxinellone was isolated from the root bark of the brassica family Dictamnus dasycarpus. Fraxinellone is a PD-L1 inhibitor that inhibits HIF-1α synthesis without affecting HIF-1α degradation. Fraxinellone has potential for cancer immunity by targeting PD-L1. |
| M4555 | Cyanidin chloride | Cyanidin chloride is a subclass of anthocyanin, displays antioxidant and anti-carcinogenesis properties, could be used for treatment of diabetes mellitus complications. |
| M4554 | Kuromanin chloride | Kuromanin 3-O-glucoside (Kuromanin chloride), derived from mulberry leaves, has the effect of increasing blood glucose concentration and maintaining lipid metabolism balance to reduce obesity. |
| M4552 | Nobiletin | Nobiletin is a citrus flavonoid with anti-inflammatory, anti-cancer, cholesterol lowering, memory protection activities. Nobiletin is a retinoid acid receptor-related orphan receptors (RORs) agonist. Nobiletin can reduce reactive oxygen species (ROS) levels in differentiated C2C12 myotubes. |
| M4551 | Trigonelline hydrochloride | Trigonelline chloride is an alkaloid with potential antidiabetic activity that can be isolated from Trigonella foenum-graecum L or Leonurus artemisia. Trigonelline chloride is a potent Nrf2 inhibitor that blocks Nrf2-dependent proteasome activity, thereby enhancing apoptosis in pancreatic cancer cells. |
| M4550 | Maslinic-acid | Maslinic-acid (MA) is a natural triterpenoid with a wide range of biological activities, such as anti-tumor, anti-diabetes, antioxidant, heart-protective, neuroprotective, anti-parasitic and growth stimulating, Maslinic acid inhibited THE DNA binding activity of NF-κB P65 and eliminated the PHOSPHORylation of IκB-α. |
| M4549 | Glucosyl-vitexin | 4 "-O-glucosylvitexin is a bioactive flavonoid extracted from hawthorn leaves. |
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