| Cat.No. | Name | Information |
|---|---|---|
| M5807 | Napabucasin (BBI608) | Napabucasin (BBI608) is a first-in-class, orally active inhibitor of Stat3 that blocks stem cell activity in cancer cells by targeting the signal transducer and activator of transcription 3 pathway. Napabucasin inhibits cell proliferation of U87MG tumor xenografts in mice. |
| M5767 | Menadione (Vitamin K3) | Menadione(Vitamin K3), a fat-soluble compound, is an inhibitor of Cdc25 phosphatase and mitochondrial DNA polymerase γ (pol γ), used as a nutritional supplement. |
| M5689 | Hesperidin | Hesperidin (HP) is a bioflavonoid that plays a role in plant defense and is abundant in citrus species, such as grapefruit, lemon and orange. Hesperidin is used effectively as a supplemental agent in complementary therapy protocols. |
| M5684 | Guaifenesin | Guaifenesin is an expectorant that also has some muscle relaxing action. |
| M5672 | Galanthamine HBr | Galanthamine HBr is an alkaloid derived from lithophyllum and also a reversible AChE inhibitor with an IC50 of 0.35 μM, which is 50-fold more selective than that used for butyrylcholinesterase. It can be used in studies related to Alzheimer's disease (AD). |
| M5549 | Danthron | Danthron functions in regulating glucose and lipid metabolism by activating AMPK. Danthron is a synthetic anthraquinone derivative, currently used as an antioxidant in synthetic lubricants, in the synthesis of antitumor agents, as a fungicide and as an intermediate for making dyes. |
| M5547 | Daidzein | Daidzein is an inactive analogue of genistein, a tyrosine kinase inhibitor and an estrogen receptor activator. |
| M5515 | Vitamin D3 | Vitamin D3 (Cholecalciferol) is a form of vitamin D, binds and activates a H305F/H397Y mutant vitamin D receptor (VDR) with EC50 of 300 nM. *The compound is unstable in solutions, freshly prepared is recommended |
| M5436 | Azelaic acid | Azelaic acid is an unsaturated fatty acid derived from plant seeds, which can also be derived from ozonolysis of oleic acid, and has antimicrobial and antioxidant activity. |
| M5422 | Ascomycin | Ascomycin (FK520), an FK-506 analog, is a neutral macrolide immunosuppressant, which prevents rejection after an organ transplant. Phase 3. |
| M5388 | Ademetionine | Ademetionine (S-adenosyl-l-methionine; SAMe) is a naturally-occurring substance which is a major source of methyl groups in the brain. Ademetionine (adenosylmethionine, S-adenosyl-L-methionine) is an orally active methyl donor utilised in studies of methylation processes involving DNA, RNA, proteins, and phospholipids. Ademetionine may also mitigate oxidative stress damage by regulating intracellular redox status. |
| M5372 | 6-Acetamidohexanoic acid | 6-Acetamidohexanoic acid is a pharmaceutical intermediate. |
| M5312 | Anacardic Acid | Anacardic Acid is a potent inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases, which also has antibacterial activity, antimicrobial activity, prostaglandin synthase inhibition, and tyrosinase and lipoxygenase inhibition. |
| M5224 | Fumagillin | Fumagillin is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis. |
| M5222 | Mertansine | Mertansine is a tubulin inhibitor，inhibits the assembly of microtubules by binding to tubulin, with a linker structure can create an antibody-drug conjugate (ADC). *The compound is unstable in solutions, freshly prepared is recommended |
| M5220 | Piperlongumine | Piperlongumine, a natural alkaloid from Piper longum L., is also a direct TrxR1 inhibitor with suppressive activity against gastric cancer and a novel inhibitor of CRM1. |
| M5185 | Xanthohumol | Xanthohumol is an inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV). |
| M5184 | Kuwanone H | Kuwanone H |
| M5181 | Gancaonin P | Gancaonin P |
| M5180 | Quercetin hydrate | Quercetin hydrate |
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