| Cat.No. | Name | Information |
|---|---|---|
| M38937 | N6-(2-Hydroxyethyl)adenosine | N6-(2-Hydroxyethyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. |
| M38935 | Oryzalin | Oryzalin is a dinitroaniline herbicide, binding to plant tubulin and inhibits microtubule (MT) polymerization in vitro. Oryzalin depolymerizes MTs and prevented the polymerization of new MTs at all stages of the mitotic cycle. |
| M38921 | Riddelline | Riddelline, a pyrrolizidine alkaloid, is a potent genotoxic agent. Riddelline induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver. |
| M38915 | Vanicoside B | Vanicoside B targets cyclin-dependent kinase 8 (CDK8) and exhibits anti-tumor activity. The potential mechanism is Vanicoside B blocks CDK8-mediated signaling pathways and decreases the expression of epithelial-mesenchymal transition proteins, so that it leads to cell cycle arrest and apoptosis. |
| M38913 | Ethephon | Ethephon is a plant growth regulator. |
| M38906 | Boc-L-proline | Boc-L-proline is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
| M38902 | 8-Aminoquinoline | 8-Aminoquinoline is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
| M38893 | Boc-L-phenylalanine | Boc-L-phenylalanine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
| M38888 | 4-Dimethylaminopyridine | 4-Dimethylaminopyridine (DMAP) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
| M38859 | 4,4'-Dimethoxychalcone | 4,4'-Dimethoxychalcone acts as a natural autophagy inducer with anti-ageing properties. |
| M38847 | Enterodiol | Enterodiol is transformed by human intestinal bacteria from lignans contained in various whole-grain cereals, nuts, legumes, flaxseed, and vegetables. Enterodiol has an apoptotic effect in colorectal cancer (CRC) cells. Anti-cancer activities. |
| M38846 | Physalin A | Physalin A induces apoptosis associated with up-regulation of caspase-3 and caspase-8 expression. Physalin A induces autophagy, found to antagonize apoptosis in HT1080 cells. Physalin A has the potential for the research of cancer disease. |
| M38828 | Alphitolic acid | Alphitolic acid (Aophitolic acid) blocks Akt–NF-κB signaling to induce apoptosis. Alphitolic acid induces autophagy. Alphitolic acid has anti-inflammatory activity and down-regulates the NO and TNF-α production. Alphitolic acid can be used for cancer and inflammation research. |
| M38826 | Cardanol monoene | Cardanol monoene (Cardanol C15:1) is a phenolic compound which can be found in cashew nut shell liquid. Cardanol monoene can induce mitochondria-associated apoptosis in human melanoma cells. |
| M38824 | Kuguaglycoside C | Kuguaglycoside C is a triterpene glycoside that induces caspase‐independent DNA cleavage and cell death of neuroblastoma cells. Kuguaglycoside C also significantly increases the expression and cleavage of apoptosis-inducing factor (AIF). |
| M38823 | Phytosphingosine | Phytosphingosine is a phospholipid and has anti-cancer activities. Phytosphingosine induces cell apoptosis via caspase 8 activation and Bax translocation in cancer cells. |
| M38807 | Umifenovir | Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against a number of enveloped and non-enveloped viruses. Umifenovir is an efficient inhibitor of SARS-CoV-2 in vitro. |
| M38800 | β-Hederin | β-Hederin, a saponin isolated from Hedera helix L.(Araliaceae), possesses antileishmanial activity. β-Hederin exhibits IC50 values of 1.5 μM, 68 nM and 4.57 μM in L. Mexicana promastigotes, L. mexicana amastigotes and THP1 cells, respectively. |
| M38795 | Homaloside D | Homaloside D is an antiplasmodial agent with an IC50 of 20 μM (11 μg/mL) against Plasmodium falciparum,W2. |
| M38767 | Abyssinone V | Abyssinone V is a prenylated flavonoid with predicted anti-viral activity. Abyssinone V is predicted to be antivirals including anti-herpes (HSV) agent, with mechanisms comprising inhibition of polymerase, ATPase and membrane integrity. |
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