| Cat.No. | Name | Information |
|---|---|---|
| M38948 | Kazinol U | Kazinol U inhibits melanogenesis through the inhibition of tyrosinase-related proteins via AMPK activation. |
| M38947 | 3α-Hydroxymogrol | 3α-Hydroxymogrol is a triterpenoid isolated from Siraitia grosvenorii Swingle, acts as a potent AMPK activator, and enhances AMPK phosphorylation. |
| M38945 | Guttiferone G | Guttiferone G inhibits recombinant human SIRT1 and SIRT2 (IC50: 9 and 22 μM, respectively). Guttiferone G is weakly cytotoxic in A2780 human ovarian cell line (IC50: 8.0 μg/mL). Guttiferone G can be isolated from Garcinia macrophylla. |
| M38944 | 3β,6α,12β-Dammar-E-20(22)-ene-3,6,12,25-tetraol | 3β,6α,12β-Dammar-E-20(22)-ene-3,6,12,25-tetraol, a SIRT1 activator, exhibits significant stimulation of SIRT1 activity. Anti-tumor activity. |
| M38943 | Caulophyllogenin | Caulophyllogenin is a triterpene saponin extracted from M. polimorpha. Caulophyllogenin is a partial PPARγ agonist, with an EC50 of 12.6 μM. Caulophyllogenin can be used for the research of type-2 diabetes, obesity, metabolic syndrome and inflammation. |
| M38942 | Dihydrobaicalein | Dihydrobaicalein is a PLK1 Inhibitor with an IC50 of 6.3 μM. Dihydrobaicalein also inhibits VRK2 and PLK2. Dihydrobaicalein is a natural product that can be isolated from Scutellaria scandens. |
| M38941 | Isoguanine | Isoguanine is a purine base that is an isomer of Guanine. A building block in organic synthesis. |
| M38940 | 3'-Deoxycytidine | 4-Amino-1-((2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one (3'-Deoxycytidine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. |
| M38939 | 6-Chloroguanineriboside | 6-Chloroguanineriboside (6-Chloroguanosine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. |
| M38938 | 5-Fluoro-5'-deoxycytidine | 5-Fluoro-5'-deoxycytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine), and have potential anti-metabolic and anti-tumor activities. |
| M38936 | N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine | N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine (5'-O-DMT-N4-Bz-dC) is an useful tool for probing enzyme-catalyzed cleavage processes in DNA. |
| M38934 | Glochidiol | Glochidiol is an orally active tubulin polymerization inhibitor with an IC50 of 2.76 μM. Glochidiol shows anti-cancer activity. |
| M38933 | Taxinine B | Taxinine B is a taxoid that can be isolated from Japanese Yew Taxus Cuspid. Taxinine B inhibits CaCl2-induced depolymerization of microtubule. Taxinine B is useful for overcoming multidrug resistance in tumor cells. |
| M38932 | 7-xylosyltaxol | 7-xylosyltaxol(Taxol-7-xyloside) is a taxol (Paclitaxel) derivative; Paclitaxel binds to tubulin and inhibits the disassembly of microtubules. |
| M38931 | Taccalonolide B | Taccalonolide B is microtubule stabilizer. Taccalonolide B is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug-resistance protein (MRP7). Taccalonolide B inhibits growth of SK-OV-3 cells with an IC50 of 208 nM. |
| M38930 | Ganoderic acid T-Q | Ganoderic acid T-Q (Ganodermic acid T-Q) (compound 1) is a natural product that can be found in ganoderma lucidum. Ganoderic acid T-Q stimulates tubulin polymerization. |
| M38929 | Curcolonol | Curcolonol is a furan type sesquiterpene. Curcolonol can be isolated from several medical herbs. Curcolonol has inhibitory activity for LIM kinase 1. Curcolonol can be used for the research of breast cancer. |
| M38928 | Feretoside | Feretoside, a phenolic compound extracted from the barks of E. ulmoides, is a HSP inducer which act as cytoprotective agent. |
| M38927 | 10,11-Dehydrocurvularin | 10,11-Dehydrocurvularin is a prevalent fungal phytotoxin and an antibiotic. 10,11-Dehydrocurvularin is a strong activator of the heat shock response. 10,11-Dehydrocurvularin inhibits TGF-β signalling pathway. Anti-tumorous activity. |
| M38926 | Pomiferin | Pomiferin (NSC 5113) acts as an potential inhibitor of HDAC, with an IC50 of 1.05 μM, and also potently inhibits mTOR (IC50, 6.2 µM). |
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