Certificate of Analysis
| Product Name: | XL-184 |
| Catalog Number: | M1757 |
| CAS Number: | 849217-68-1 |
Physical and Chemical Properties
| Formula: | C28H24FN3O5 |
| Molecular Weight: | 501.51 |
| Solubility: | DMSO 50 mg/mL |
| Storage: | 2-8°C, protect from light |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.38% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Cabozantinib (XL184, BMS-907351) is a small molecule inhibits multiple receptor tyrosine kinases, specifically MET and VEGFR2 with IC50 values of 0.035 and 1.8 nM for VEGFR2 and Met respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |