Certificate of Analysis
| Product Name: | Uprosertib (GSK2141795) |
| Catalog Number: | M6044 |
| CAS Number: | 1047634-65-0 |
Physical and Chemical Properties
| Formula: | C18H16Cl2F2N4O2 |
| Molecular Weight: | 429.25 |
| Solubility: | DMSO 30 mg/mL |
| Storage: | -20°C, sealed |
| Chemical Structure: | .gif) |
Analytical Data
| QC Standard: | 98.21% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Uprosertib (GSK2141795) is a potent and selective pan-Akt inhibitor with IC50 values of 180 nM for Akt1, 328 nM for Akt2, and 38 nM for Akt3 respectively (Clinical phase 1). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |