Certificate of Analysis
| Product Name: | UNC1999 |
| Catalog Number: | M3107 |
| CAS Number: | 1431612-23-5 |
Physical and Chemical Properties
| Formula: | C33H43N7O2 |
| Molecular Weight: | 569.74 |
| Solubility: | DMSO 80 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 100.00% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | UNC1999 is a potent, orally bioavailable and selective inhibitor of EZH2 and EZH1 with IC50 of 2 nM and 45 nM, respectively, showing >1000-fold selectivity over a broad range of epigenetic and non-epigenetic targets. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |