| Product Name: | Tris(2-carboxyethyl)phosphine hydrochloride |
| Catalog Number: | M7529 |
| CAS Number: | 51805-45-9 |
| Formula: | C9H15O6P·HCl |
| Molecular Weight: | 286.65 |
| Solubility: | 45 mg/mL in water (adjust pH with NaOH); DMSO 90 mg/mL |
| Storage: | 2-8°C, protect from light, sealed |
| Chemical Structure: | ![]() |
| Description: | TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a faster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively reduces protein disuldes without altering the properties or interacting with thiol-directed agents in the reaction mixture. TCEP hydrochloride is also a commonly used reducing agent in the DNA/AuNP chemistry. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |