Certificate of Analysis
| Product Name: | THZ1 Hydrochloride |
| Catalog Number: | M13617 |
Physical and Chemical Properties
| Molecular Weight: | 602.51 |
| Solubility: | DMSO 22.5 mg/mL |
| Storage: | 2-8°C, dry, sealed |
| Chemical Structure: |  |
Product Information
| Description: | THZ1 Hydrochloride is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM. THZ1 Hydrochloride also inhibits the closely related kinases CDK12 and CDK13 and downregulates MYC expression. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |