Certificate of Analysis
| Product Name: | Tacrolimus monohydrate |
| Catalog Number: | M6293 |
| CAS Number: | 109581-93-3 |
Physical and Chemical Properties
| Formula: | C44H71NO13 |
| Molecular Weight: | 822.03 |
| Solubility: | 10 mM in DMSO |
| Storage: | 2-8°C, protect from light |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 98.11% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Tacrolimus monohydrate binds to FK506 binding protein (FKBP). This complex inhibits calcineurin phosphatase (PP2B). Tacrolimus monohydrate is a mTOR-independent autophagy inducer. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |