| Product Name: | Spexin |
| Catalog Number: | M25558 |
| CAS Number: | 1370290-58-6 |
| Formula: | C74H114N20O19S |
| Molecular Weight: | 1619.88 |
| Form: | Solid |
| Solubility: | Water 20 mg/mL |
| Storage: | Store at ≤ -20°C, protect from light, dry, sealed |
| Description: | Spexin (Neuropeptide Q) is a selective agonist of galanin receptors GAL2 and GAL3. Spexin is a conserved peptide plays roles of neurotransmitter/neuromodulator and endocrine factor. Spexin upregulates Beclin 1 to inhibit ferroptosis induced by excessive autophagy, reduces the uptake of long-chain fatty acids by adipocytes, and regulates energy metabolism by increasing lipid oxidation (e.g., reducing the respiratory exchange ratio in rodents). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |