Certificate of Analysis
| Product Name: | SIS3 hydrochloride |
| Catalog Number: | M8149 |
| CAS Number: | 521984-48-5 |
Physical and Chemical Properties
| Formula: | C28H27N3O3.HCl |
| Molecular Weight: | 489.99 |
| Solubility: | DMSO: ≥ 70 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.53% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | SIS3 hydrochloride is a novel specific inhibitor of TGF-β1/ALK-5 phosphorylation of Smad3 with an IC50 of 3 µM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |