Certificate of Analysis
| Product Name: | SIS3 |
| Catalog Number: | M59151 |
| CAS Number: | 521985-36-4 |
Physical and Chemical Properties
| Formula: | C28H27N3O3 |
| Molecular Weight: | 453.53 |
| Solubility: | DMSO 90 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Product Information
| Description: | SIS3 is a potent and selective inhibitor of Smad3 phosphorylation. SIS3 inhibits the myofibroblast differentiation of fibroblasts by TGF-β1. SIS3 does not affect the phosphorylation of Smad2. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |