Certificate of Analysis
| Product Name: | Poziotinib |
| Catalog Number: | M5031 |
| CAS Number: | 1092364-38-9 |
Physical and Chemical Properties
| Formula: | C23H21Cl2FN4O3 |
| Molecular Weight: | 491.34 |
| Solubility: | 10 mM in DMSO |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 98.63% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Poziotinib (NOV120101; HM781-36B) is an irreversible Pan-HER inhibitor with IC50s of 3/5/23 nM for HER1/HER2/HER4 respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |